Overview
Catalog No.
RHB52602
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
E3 ubiquitin-protein ligase UBR5, hHYD, EDD, KIAA0896, E3 ubiquitin-protein ligase, HECT domain-containing 1, HYD, EDD1, HECT-type E3 ubiquitin transferase UBR5, UBR5, Progestin-induced protein, Hyperplastic discs protein homolog
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95071
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2W14
Data Image
References
EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer., PMID:39905540
UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD., PMID:32558906
Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab., PMID:30647455
Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins., PMID:29764992
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells., PMID:25470037
A functional genomic approach reveals the transcriptional role of EDD in the expression and function of angiogenesis regulator ACVRL1., PMID:24189493
Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs., PMID:10030672
Datasheet
For research use only. Not for human or drug use.
