Catalog No.
RHB40802
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
Caspase-activated nuclease, DFF2, Caspase-activated DNase, CAD, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor subunit beta, Caspase-activated deoxyribonuclease, DFF40, DFFB, DFF-40, CPAN
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O76075
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2W04
Design and characterization of a recombinant immunotoxin for targeted therapy of breast cancer cells: In vitro and in silico analyses., PMID:33301810
Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice., PMID:28007744
Safeguarding Stem Cell-Based Regenerative Therapy against Iatrogenic Cancerogenesis: Transgenic Expression of DNASE1, DNASE1L3, DNASE2, DFFB Controlled By POLA1 Promoter in Proliferating and Directed Differentiation Resisting Human Autologous Pluripotent Induced Stem Cells Leads to their Death., PMID:25045589
Eradication of Human Ovarian Cancer Cells by Transgenic Expression of Recombinant DNASE1, DNASE1L3, DNASE2, and DFFB Controlled by EGFR Promoter: Novel Strategy for Targeted Therapy of Cancer., PMID:24587967
GM-CSF-DFF40: a novel humanized immunotoxin induces apoptosis in acute myeloid leukemia cells., PMID:23529188
[Repressional effects of the glutamate antibodies on expression of Dffb gene in the brain of rats with experimental Alzheimer's disease]., PMID:23156675
TPCK-induced apoptosis and labelling of the largest subunit of RNA polymerase II in Jurkat cells., PMID:19653099
Generation of aberrant forms of DFF40 concurrent with caspase-3 activation during acute and chronic liver injury in rats., PMID:17011520
Oligomerization state of the DNA fragmentation factor in normal and apoptotic cells., PMID:16204257
Coordinate expression of apoptosis-associated proteins in human breast cancer before and during chemotherapy., PMID:12114409
Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins., PMID:11606398
For research use only. Not for human or drug use.
