Catalog No.
RHB17203
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:20-1:100
Target
Histone macroH2A1, mH2A1, H2A/y, MACROH2A1, Medulloblastoma antigen MU-MB-50.205, Core histone macro-H2A.1, H2AFY, Histone H2A.y
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O75367
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2V67
Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1., PMID:39545415
Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma., PMID:39255035
Integrated spatial genomics reveals global architecture of single nuclei., PMID:33505024
The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate., PMID:28564596
MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis., PMID:25526730
Distinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domains., PMID:23118866
X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2., PMID:21738686
The histone H2A variant macroH2A1 does not localize to the centrosome., PMID:21364955
Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome., PMID:18936163
Epigenetic processes in a tetraploid mammal., PMID:18758856
A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis., PMID:18227505
Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist., PMID:12356914
Histone macroH2A1 is concentrated in the inactive X chromosome of female preimplantation mouse embryos., PMID:10804171
Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals., PMID:9634239
Developmental and tissue expression patterns of histone macroH2A1 subtypes., PMID:9138085
For research use only. Not for human or drug use.
