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Anti-KDM4A Antibody (R2V58)

Catalog #:   RHB11506 Specific References (14) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF
Accession: O75164
Overview

Catalog No.

RHB11506

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Lysine-specific demethylase 4A, JMJD2, Jumonji domain-containing protein 2A, KDM4A, KIAA0677, JHDM3A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, JMJD2A, JmjC domain-containing histone demethylation protein 3A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O75164

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2V58

Data Image
  • Immunofluorescence
    Immunofluorescence analysis of HeLa cells using KDM4A mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunofluorescence
    Immunofluorescence analysis of HeLa cells using KDM4A mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
References

Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723

RETRACTED: KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/β-catenin signaling pathway., PMID:33002480

RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A., PMID:32883983

Circ_SPECC1 enhances the inhibition of miR-526b on downstream KDM4A/YAP1 pathway to regulate the growth and invasion of gastric cancer cells., PMID:31349968

Novel inhibitors of lysine (K)-specific Demethylase 4A with anticancer activity., PMID:28905188

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication., PMID:28212444

The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations., PMID:28051298

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy., PMID:27612013

Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine., PMID:27171244

KDM4A, KDM4B and KDM4C in non-small cell lung cancer., PMID:26722485

Tetrazolylhydrazides as Selective Fragment-Like Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A., PMID:26337137

Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry., PMID:20583823

Diversity within the JMJD2 histone demethylase family., PMID:17207460

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein., PMID:15927959

Datasheet

Document Download

Anti-KDM4A Antibody (R2V58).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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For research use only. Not for human or drug use.

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Anti-KDM4A Antibody (R2V58) [RHB11506]
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