Catalog No.
RHA89002
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
KIAA0603, TBC1D4, Akt substrate of 160 kDa, AS160, TBC1 domain family member 4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O60343
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2V22
Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects., PMID:23344726
Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney., PMID:22466139
Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle., PMID:22318952
Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion., PMID:22139838
Negative regulation of adiponectin secretion by receptor interacting protein 140 (RIP140)., PMID:21872658
In vivo exercise followed by in vitro contraction additively elevates subsequent insulin-stimulated glucose transport by rat skeletal muscle., PMID:20179245
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle., PMID:19923418
Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle., PMID:19252894
Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle., PMID:19208911
Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery., PMID:18845784
Contraction-stimulated glucose transport in rat skeletal muscle is sustained despite reversal of increased PAS-phosphorylation of AS160 and TBC1D1., PMID:18818383
Globular adiponectin stimulates glucose transport in type 2 diabetic muscle., PMID:18615850
Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle., PMID:18276596
Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes., PMID:18215134
Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle., PMID:16731842
For research use only. Not for human or drug use.
