Catalog No.
RHA70201
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:2000
Target
hSMAD6, MAD homolog 6, SMAD family member 6, SMAD 6, Mothers against decapentaplegic homolog 6, SMAD6, Mothers against DPP homolog 6, MADH6, Smad6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O43541
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2U92
Prevalence of Inflammatory Pathways Over Immuno-Tolerance in Peripheral Blood Mononuclear Cells of Recent-Onset Type 1 Diabetes., PMID:35058920
IFNβ signaling inhibits osteogenesis in human SLE bone marrow., PMID:32515653
MicroRNA-31/184 is involved in transforming growth factor-β-induced apoptosis in A549 human alveolar adenocarcinoma cells., PMID:31874165
Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each., PMID:30418981
Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis., PMID:23620745
Co-expression of BMPs and BMP-inhibitors in human fractures and non-unions., PMID:22521262
Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence., PMID:22072987
Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/beta-catenin pathway., PMID:21730158
[Gene expression of OAZ pathway in the patients of systemic lupus erythematosus]., PMID:20017333
Hoxc8 represses BMP-induced expression of Smad6., PMID:20016939
BMP-2 signaling in ovarian cancer and its association with poor prognosis., PMID:19366455
Effect of interleukin-1beta on osteogenic protein 1-induced signaling in adult human articular chondrocytes., PMID:19116903
BMP-7 protects mesangial cells from injury by polymeric IgA., PMID:18496506
Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells., PMID:18414391
SMAD expression in the testis: an insight into BMP regulation of spermatogenesis., PMID:18069690
Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells., PMID:17962458
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation., PMID:16860915
A novel vitamin D derivative activates bone morphogenetic protein signaling in MCF10 breast epithelial cells., PMID:16533909
BMP-4 induces a Smad-dependent apoptotic cell death of mouse embryonic stem cell-derived neural precursors., PMID:16311513
[Protection of rosiglitazone against renal interstitial lesion and its mechanism]., PMID:16185530
Prognostic value of the expression of Smad6 and Smad7, as inhibitory Smads of the TGF-beta superfamily, in esophageal squamous cell carcinoma., PMID:15736400
Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor., PMID:15296834
Interaction of Smad3 and SRF-associated complex mediates TGF-beta1 signals to regulate SM22 transcription during myofibroblast differentiation., PMID:14654367
Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3., PMID:12815042
Developmental expression of Smad1-7 suggests critical function of TGF-beta/BMP signaling in regulating epithelial-mesenchymal interaction during tooth morphogenesis., PMID:12653249
Localization of Smad6 and Smad7 in the rat kidney and their regulated expression in the anti-Thy-1 nephritis., PMID:11170839
For research use only. Not for human or drug use.
