Catalog No.
RHA43901
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:50-1:250
Target
AXIN, Axin-1, hAxin, Axis inhibition protein 1, AXIN1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O15169
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2U44
Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers., PMID:40442146
A novel drug prejudice scaffold-imidazopyridine-conjugate can promote cell death in a colorectal cancer model by binding to β-catenin and suppressing the Wnt signaling pathway., PMID:39067696
Inflammatory related plasma proteins involved in acute preschool wheeze., PMID:38006384
Nogo-B deficiency suppresses white adipogenesis by regulating β-catenin signaling., PMID:36931495
TSH receptor antibodies (TRAb) - A potential new biomarker for endometriosis., PMID:36152376
Mechanisms of miR‑128‑3p in inhibiting osteoblast differentiation from bone marrow‑derived mesenchymal stromal cells., PMID:33174052
Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance)., PMID:32958699
The Immunome of Colon Cancer: Functional In Silico Analysis of Antigenic Proteins Deduced from IgG Microarray Profiling., PMID:29505855
Long noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) inhibits proliferation and invasion of glioma cells by suppressing the Wnt/β-catenin signaling pathway., PMID:28187755
Aptamer-Targeted Attenuation of IL-2 Signaling in CD8+ T Cells Enhances Antitumor Immunity., PMID:28129128
The destruction complex of beta-catenin in colorectal carcinoma and colonic adenoma., PMID:27462886
Protein Profile and Morphological Alterations in Penumbra after Focal Photothrombotic Infarction in the Rat Cerebral Cortex., PMID:27324898
The prostate cancer immunome: In silico functional analysis of antigenic proteins from microarray profiling with IgG., PMID:27089054
Tissue inhibitor of metalloproteinase 2 inhibits activation of the β-catenin signaling in melanoma cells., PMID:25839957
The increase in maternal expression of axin1 and axin2 contribute to the zebrafish mutant ichabod ventralized phenotype., PMID:25335865
Human Sarcoma growth is sensitive to small-molecule mediated AXIN stabilization., PMID:24842792
A quantitative trait locus for a primary antibody response to keyhole limpet hemocyanin on chicken chromosome 14--confirmation and candidate gene approach., PMID:20709969
The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres., PMID:20691072
Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma., PMID:18497987
Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma., PMID:18384130
Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6., PMID:18362152
WNT signaling pathway and stem cell signaling network., PMID:17634527
Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer., PMID:16273202
Mutations of the APC, beta-catenin, and axin 1 genes and cytoplasmic accumulation of beta-catenin in oral squamous cell carcinoma., PMID:16163548
Infrequent mutation of APC, AXIN1, and GSK3B in human pituitary adenomas with abnormal accumulation of CTNNB1., PMID:15981102
Domains of axin and disheveled required for interaction and function in wnt signaling., PMID:11027605
Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling., PMID:10512857
For research use only. Not for human or drug use.
