Catalog No.
VRD36901
Species reactivity
Rat
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Ig kappa chain C region EU, Ig kappa chain C region, Ig kappa chain C region ROY, Immunoglobulin kappa constant, IGKC, Ig kappa chain C region TI, Ig kappa chain C region OU, Ig kappa chain C region CUM, Ig kappa chain C region AG
Concentration
1 mg/ml
Endotoxin level
< 1 EU/mg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, In vivo Functional Assay
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
MAR 18.5
Protocols for circulating neutrophil depletion in neonatal C57Bl/6 mice., PMID:39282419
Protective effect of modified Huangqi Chifeng decoction on immunoglobulin A nephropathy through toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-kappa B signaling pathway., PMID:38504538
Effect of Infliximab on Radiation-Induced Submandibular Gland Dysfunction in Rats., PMID:38044712
The presence of Mott cells in the lymph nodes of rats with experimental autoimmune encephalomyelitis., PMID:37952208
Placenta-Derived Extracellular Vesicles From Preeclamptic Pregnancies Impair Vascular Endothelial Function via Lectin-Like Oxidized LDL Receptor-1., PMID:37615097
Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome., PMID:37587118
Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling., PMID:37551407
DhHP-6 alleviates inflammation and reduces vascular permeability by eliminating reactive oxygen species., PMID:37533406
Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies., PMID:37167766
Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion., PMID:37015912
Acetate: A therapeutic candidate against renal disorder in a rat model of polycystic ovarian syndrome., PMID:36150640
Exploring the mechanism of Qinbaiqingfei-concentrate pills in the treatment of Mycoplasma pneumoniae pneumonia from the perspective of intestinal microbiota and mucosal immunity., PMID:35460847
Identification of contagious SARS-CoV-2 infected individuals by Roche's Rapid Antigen Test., PMID:35258234
A Recombinant Ig Fragment (IgCw-γεκ) Comprising the Cγ1-Cε2-4 and Cκ Domains Is an Alternative Reagent to Human IgE., PMID:35022271
Etanercept Mitigates Cadmium Chloride-induced Testicular Damage in Rats "An Insight into Autophagy, Apoptosis, Oxidative Stress and Inflammation"., PMID:34993805
WNT1-inducible signaling pathway protein 1 regulates kidney inflammation through the NF-κB pathway., PMID:34897418
Microglia-derived TNF-α mediates Müller cell activation by activating the TNFR1-NF-κB pathway., PMID:34801535
Taurine Alleviates Sympathetic Innervation by Inhibiting NLRP3 Inflammasome in Postinfarcted Rats., PMID:34057159
Orange peel extract reduces the inflammatory state of skeletal muscle after downhill running via an increase in IL-1RA., PMID:33739383
Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in rats., PMID:33576458
A rat model expressing a human amyloidogenic kappa light chain., PMID:33480298
A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats., PMID:33154441
The Transcription Factor NF-κB Mediates Thyrotropin-Stimulated Expression of Thyroid Differentiation Markers., PMID:32935630
Naringin ameliorates type 2 diabetes mellitus-induced steatohepatitis by inhibiting RAGE/NF-κB mediated mitochondrial apoptosis., PMID:32702445
Development of a Chimeric Antigen-Binding Fragment Directed Against Human Galectin-3 and Validation as an Immuno-Positron Emission Tomography Tracer for the Sensitive In Vivo Imaging of Thyroid Cancer., PMID:32200708
Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing., PMID:31980672
Downregulation of TNF-α/TNF-R1 Signals by AT-Lipoxin A4 May Be a Significant Mechanism of Attenuation in SAP-Associated Lung Injury., PMID:31097921
Tanshinone IIA inhibits lipopolysaccharide‑induced inflammatory responses through the TLR4/TAK1/NF‑κB signaling pathway in vascular smooth muscle cells., PMID:30816448
Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model., PMID:30810635
Liraglutide inhibited AGEs induced coronary smooth muscle cell phenotypic transition through inhibiting the NF-κB signal pathway., PMID:30513352
Group II innate lymphoid cells and microvascular dysfunction from pulmonary titanium dioxide nanoparticle exposure., PMID:30413212
Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli., PMID:30347409
Improved RANKL production by memory B cells: A way for B cells promote alveolar bone destruction during periodontitis., PMID:30199848
NF-kB mediated CX3CL1 activation in the dorsal root ganglion contributes to the maintenance of neuropathic pain induced in adult male Sprague Dawley rats1., PMID:30110063
Effects of Flower Buds Extract of Tussilago farfara on Focal Cerebral Ischemia in Rats and Inflammatory Response in BV2 Microglia., PMID:30090976
Nuclear factor kappa B regulated monocyte chemoattractant protein-1/chemokine CC motif receptor-2 expressing in spinal cord contributes to the maintenance of cancer-induced bone pain in rats., PMID:29956585
The roles of the TLR/NF‑κB signaling pathway in the mutual interactions between the lung and the large intestine., PMID:29901105
Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies., PMID:29740455
TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways., PMID:29702085
Molecular Mechanism of MiR-136-5p Targeting NF-κB/A20 in the IL-17-Mediated Inflammatory Response after Spinal Cord Injury., PMID:29179211
Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis., PMID:29165430
Which one is more effective for the treatment of rat sepsis model: thalidomide or etanercept?, PMID:28516791
Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway., PMID:28187436
Chimeric Anti-Human Podoplanin Antibody NZ-12 of Lambda Light Chain Exerts Higher Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity Compared with NZ-8 of Kappa Light Chain., PMID:28157429
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway., PMID:28073079
MD2 mediates angiotensin II-induced cardiac inflammation and remodeling via directly binding to Ang II and activating TLR4/NF-κB signaling pathway., PMID:28013347
Advanced glycation end products interfere with gastric smooth muscle contractile marker expression via the AGE/RAGE/NF-κB pathway., PMID:27939576
Trikatu, an herbal compound ameliorates rheumatoid arthritis by the suppression of inflammatory immune responses in rats with adjuvant-induced arthritis and on cultured fibroblast like synoviocytes via the inhibition of the NFκB signaling pathway., PMID:27613480
Salusin-β contributes to vascular inflammation associated with pulmonary arterial hypertension in rats., PMID:27353339
The pro-apoptotic effects of TIPE2 on AA rat fibroblast-like synoviocytes via regulation of the DR5-caspase-NF-κB pathway in vitro., PMID:27013892
For research use only. Not for human or drug use.
