InVivoMAb Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114)

Catalog No.

VMM03601

Species reactivity

Mouse

Host species

Rat

Isotype

IgG2b

Clonality

Monoclonal

Target

MHC Class II, I-A/I-E, I-A, I-E

Concentration

1 mg/ml

Endotoxin level

< 1 EU/mg as determined by LAL test.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

ELISA, In vivo Functional Assay

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

M5/114

Immunoinformatics-Aided Design of a Multiepitope Vaccine Against Eimeria Tenella-Associated Chicken Coccidiosis., PMID:40535025

Elucidation of B-cell specific drug immunogenicity liabilities via a novel ex vivo assay., PMID:40534885

IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in Jak2 V617F clonal hematopoiesis-driven atherosclerosis., PMID:40501724

Two major human phenotypes of MICA molecules and their differential activation to NK cells via NKG2D receptor., PMID:40458406

Associations between HLA-II variation and antibody specificity are predicted by antigen properties., PMID:40457459

Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation., PMID:40421016

The Validation of Antibodies Suitable for Flow Cytometric Analysis and Immunopeptidomics of Peptide-MHC Complexes in the Outbred Swiss Albino Mouse Strain., PMID:40407470

CD83 suppresses endogenous March-I-dependent MHC class II ubiquitination, endocytosis, and degradation., PMID:40397676

Blocking plasma cell fate enhances antigen-specific presentation by B cells to boost anti-tumor immunity., PMID:40360528

Rabies vaccination induces a CD4+ TEM and CD4+CD8+ TEMRA TH1 phenotype in dogs., PMID:40354406

Regulatory T cell epitope content in human antibodies decreases during maturation., PMID:40313951

Over-expression of Truncated IK Ameliorates Dinitrochlorobenzene-Induced Allergic Contact Dermatitis Lesions in BALB/c Mice., PMID:40294983

The Influence of the Germline HSD3B1 Adrenal-Permissive Allele (c.1100 C) on the Somatic Alteration Landscape, the Transcriptome, and Immune Cell Infiltration in Prostate Cancer., PMID:40282446

B cell-expressed CD1d promotes MPL/TDCM lipid emulsion adjuvant effects in polysaccharide vaccines., PMID:40280183

Engineering a multi-epitope chimera derived from Acinetobacter baumannii CAM87009.1 and FilF fimbriae proteins: immunogenic and antibiofilm activity., PMID:40274757

Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis., PMID:40270956

Disentangling effects of the DR and DQ isomers encoded by the HLA class II haplotype DRB1*15:01/DQB1*06:02 to help establish the true risk allele for FVIII inhibitor development in Hemophilia A., PMID:40270541

In-silico and experimental analysis of Klebsiella pneumoniae fimbriae subunits for vaccine development., PMID:40203594

Cross-variant immune shield: computational multiepitope vaccine design against B.617.2 to Omicron sub-lineages in SARS-CoV-2., PMID:40202023

MHC class II-mediated spontaneous rejection of breast carcinomas expressing model neoantigens., PMID:40187751

Bibliometric analysis of Helicobacter pylori vaccine development from 1993 to 2023., PMID:40165784

Designing a Multi-Epitope Vaccine Candidate for Visceral Leishmaniasis Targeting Leishmania and Sand Fly Vector Antigens: An In Silico Approach., PMID:40154672

Genetic Polymorphisms in MHC Classes I and II Predict Outcomes in Metastatic Colorectal Cancer., PMID:40141198

Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs., PMID:40101708

De Novo donor-specific anti-HLA antibody risk stratification in kidney transplantation using a combination of B cell and T cell molecular mismatch assessment., PMID:40070832

Sex and Age-Based Differences in Immune Responses to a Peptide Vaccine for Melanoma in Two Clinical Trials., PMID:40006740

Atopic skin inflammation promotes systemic anaphylactic responses via IL-13 signaling in conventional dendritic cells., PMID:39989951

Immunoglobulin gene expression as a biomarker for Streptococcosis resistance in Nile tilapia (Oreochromis niloticus)., PMID:39952310

Cutting to the chase: Pruning alloreactive T cells., PMID:39938479

Immunohistochemical identification of immune cell subsets in formalin- and zinc-fixed, paraffin-embedded tissues from chicken and duck using commercial antibodies., PMID:39938274

AQP4-specific T cells determine lesion localization in the CNS in a model of NMOSD., PMID:39934927

Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population., PMID:39906739

Sustained T cell-independent type 2 antibody response in a naturally MHC II-deficient teleost fish., PMID:39892681

Identification of indirect CD4+ T cell epitopes associated with transplant rejection provides a target for donor-specific tolerance induction., PMID:39889703

Antibody ligation of HLA class II induces YAP nuclear localization and formation of cytoplasmic YAP condensates in human endothelial cells., PMID:39865973

Characterization of Dendritic Cells and Myeloid-Derived Suppressor Cells Expressing Major Histocompatibility Complex Class II in Secondary Lymphoid Organs in Systemic Lupus Erythematosus-Prone Mice., PMID:39769367

The HIP mouse and all of its organs are completely invisible to allogeneic immune cells., PMID:39758817

A general system for targeting MHC class II-antigen complex via a single adaptable loop., PMID:39672953

FVIII peptides presented on HLA-DP and identification of an A3 domain peptide binding with high affinity to the commonly expressed HLA-DP4., PMID:39665218

Expression and delivery of HA1-M2e antigen using an innovative attenuated Salmonella-mediated delivery system confers promising protection against H9N2 avian influenza challenge., PMID:39631285

Impaired SARS-CoV-2-Specific CD8+ T Cells After Infection or Vaccination but Robust Hybrid T Cell Immunity in Patients with Multiple Myeloma., PMID:39591152

Non-RBD peptides of SARS-CoV-2 spike protein exhibit immunodominance as they elicit both innate and adaptive immune responses., PMID:39568852

Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity., PMID:39547420

Ubiquitination and degradation of MHC-II by Tim-3 inhibits antiviral immunity., PMID:39546827

B-cell and plasma cell activation in a mouse model of chronic muscle pain., PMID:39507010

Antigen-specific modulation of chronic experimental autoimmune encephalomyelitis in humanized mice by TCR-like antibody targeting autoreactive T-cell epitope., PMID:39496501

Oxymatrine attenuates chronic allograft rejection by modulating immune responses and inhibiting fibrosis., PMID:39486768

Association of human leucocyte antigen loci with vaccine-induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4-derived peptides and MHC-II., PMID:39462764

Distinct Non-Human Leukocyte Antigen Antibody Signatures Correlate with Endothelial Crossmatch Status in Lung and Renal Transplant Recipients., PMID:39408890

Imaging the immune sequelae of infection with SARS-CoV-2 in nonhuman primates by using two nanobody PET-tracers., PMID:39400953

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