Catalog No.
VMB96002
Species reactivity
Mouse
Host species
Rat
Isotype
IgG2b, kappa
Clonality
Monoclonal
Target
Cd8a, T-cell surface glycoprotein CD8 alpha chain, Lyt-2, CD8a, Lyt2, T-cell surface glycoprotein Lyt-2
Concentration
1 mg/ml
Endotoxin level
< 1 EU/mg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, In vivo CD8+ T cell Depletion,WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
2.43
Development of a CD3ε mAb that can identify and in vitro activate T cells in large yellow croaker (Larimichthyscrocea)., PMID:40449701
Targeting CD8+ T cells in cardiovascular diseases - current options and therapeutic perspectives., PMID:40448685
Eliciting Dual-Niche Immunological Priming by Acupoint Delivery of Nanovaccines., PMID:40434536
Expanding the CAR toolbox with high throughput screening strategies for CAR domain exploration: a comprehensive review., PMID:40210240
Immunological Responses and Protection in the Largemouth Bass (Microterus salmoides) Immunized with Inactivated Vaccine Against Largemouth Bass Ranavirus (LMBRaV)., PMID:40150332
Evaluation of immunological effects of two DNA vaccines against Nocardia seriolae in hybrid snakehead., PMID:40058678
CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity., PMID:40046047
Composition and function of AChR chimeric autoantibody receptor T cells for antigen-specific B cell depletion in myasthenia gravis., PMID:40020066
Comparative analysis of immunogenicity for viral hemorrhagic septicemia virus (VHSV) vaccines inactivated by different methods., PMID:39986583
PET Imaging of PD-L1 Occupancy for Preclinical Assessment of the Efficacy of Combined Anti-PD-L1 Immunotherapy and Targeted Therapy., PMID:39978814
Construction of Heme-Binding Protein Deleted Strain and Using It as an Attenuated Vaccine Against Nocardia seriolae in Hybrid Snakehead (Channa maculata ♀ × Channa argus ♂)., PMID:39945098
Construction and analysis of the immune effect of subunit vaccines based on the flagellin FlaB and FlaC of Vibrioharveyi., PMID:39826628
Ontogeny of the organized nasopharynx-associated lymphoid tissue in rainbow trout., PMID:39643071
Solving technical issues in flow cytometry to characterize porcine CD8α/β expressing lymphocytes., PMID:39500097
Cell-mediated and humoral immune responses of cyprinids induced by a live attenuated vaccine against cyprinid herpesvirus 2 infection in comparison to the virus non-permissive high temperature water treatment., PMID:39477169
Minimally Modified HIV-1 Infection of Macaques: Development, Utility, and Limitations of Current Models., PMID:39459950
Outer membrane vesicles (OMVs) from Tenacibaculum maritimum as a potential vaccine against fish tenacibaculosis., PMID:39370018
Evaluation of inflammatory biomarkers and their association with anti-SARS-CoV-2 antibody titers in healthcare workers vaccinated with BNT162B2., PMID:39247198
Development of bioassay platforms for biopharmaceuticals using Jurkat-CAR cells by AICD., PMID:39197208
Antibody feedback regulation., PMID:39180190
PruΔcdpk2 Protects Pigs Against Acute Toxoplasmosis Depending on T-Lymphocyte Subsets and Natural Killer Cell Responses., PMID:39133119
Discrimination of Jamaican fruit bat lymphocytes by flow cytometry., PMID:39071331
CD4+CD8αlow T Cell Clonal Expansion Dependent on Costimulation in Patients With Rheumatoid Arthritis., PMID:39054665
Development and evaluation of immunological effects of a DNA vaccine encoding phosphoketolase family protein against Nocardia seriolae in hybrid snakehead., PMID:39019124
Investigation of activation-induced markers (AIM) in porcine T cells by flow cytometry., PMID:38868498
Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models., PMID:38605414
Targeting pathogenic CD8+ tissue-resident T cells with chimeric antigen receptor therapy in murine autoimmune cholangitis., PMID:38580644
Antibody-mediated depletion of select leukocyte subsets in blood and tissue of nonhuman primates., PMID:38529287
Antibody-mediated depletion of select T cell subsets in blood and tissue of nonhuman primates., PMID:38187627
Chimeric antigen receptor T cells to target CD79b in B-cell lymphomas., PMID:38007239
Huaier improves the efficacy of anti-PD-L1 Ab in the treatment of hepatocellular carcinoma by regulating tumor immune microenvironment., PMID:37984124
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models., PMID:37924157
Primary tumor-induced immunity suppresses bone metastases of breast cancer in syngeneic immunocompetent mouse models., PMID:37863157
CD8+ lymphocytes are critical for early control of tuberculosis in macaques., PMID:37843832
Ascaridia galli infection in chicken: Pathobiology and immunological orchestra., PMID:37773698
Intravital Imaging of Intestinal Intraepithelial Lymphocytes., PMID:37497460
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy., PMID:37310382
Construction of an alanine dehydrogenase gene deletion strain for vaccine development against Nocardia seriolae in hybrid snakehead (Channa maculata ♀ × Channa argus ♂)., PMID:37207887
Boosting Live Malaria Vaccine with Cytomegalovirus Vector Can Prolong Immunity through Innate and Adaptive Mechanisms., PMID:37205446
Immune Response Against SARS-CoV-2 Infection and Vaccination in a CD8α-Deficient Patient., PMID:37145391
Directed targeting of B-cell maturation antigen-specific CAR T cells by bioinformatic approaches: From in-silico to in-vitro., PMID:37058845
Spontaneous development of an autoimmune hepatitis - primary biliary cholangitis overlap syndrome in dnTGFβRII Aire-/- mice., PMID:36853094
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection., PMID:36798517
INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses., PMID:36653071
Spatially Characterizing the Immune Contexture in Mouse Tissue Using Multiplex Immunohistochemistry., PMID:36513940
A Novel Organized Nasopharynx-Associated Lymphoid Tissue in Teleosts That Expresses Molecular Markers Characteristic of Mammalian Germinal Centers., PMID:36426979
Cholesterol accumulation on dendritic cells reverses chronic hepatitis B virus infection-induced dysfunction., PMID:36369367
Immune Enhancement of Nanoparticle-Encapsulated Ginseng Stem-Leaf Saponins on Porcine Epidemic Diarrhea Virus Vaccine in Mice., PMID:36366319
Modification of Hinge/Transmembrane and Signal Transduction Domains Improves the Expression and Signaling Threshold of GXMR-CAR Specific to Cryptococcus spp., PMID:36359781
Immune-enhancing effects of Astragalus polysaccharides and Ganoderma lucidum polysaccharides on Vibrio harveyi flgJ DNA vaccine in grouper., PMID:36352832
For research use only. Not for human or drug use.
