Catalog No.
VMH28803
Species reactivity
Mouse
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Il17a, Ctla8, IL-17, IL-17A, Interleukin-17A, CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, Il17
Concentration
1 mg/ml
Endotoxin level
< 1 EU/mg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, In vivo Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
17F3
Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model., PMID:40529585
[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340
An evaluation of bimekizumab for the treatment of hidradenitis suppurativa., PMID:40524676
Immune Characterization of a Vietnamese Cohort With Idiopathic Inflammatory Myopathies., PMID:40521794
Investigation of the Efficacy and Safety of Xeligekimab (GR1501) in Patients with Moderate-to-Severe Plaque Psoriasis: A Multicenter, Randomized, Double-Blind Phase II Clinical., PMID:40517362
Selected cytokine and chemokine concentrations in equine autologous conditioned serum are similar under defined and practically relevant storage conditions., PMID:40496923
The role of IL-17-related signaling in myelomagenesis, disease prognosis/progression, and therapeutic approach-a scoping review., PMID:40488820
Severity of psoriasis and its impact on patient-reported outcomes (PROs): real world evidence with brodalumab 210 mg from the LIBERO study., PMID:40485500
Genetic deletion of microsomal prostaglandin E synthase-1 promotes imiquimod-induced psoriasis in mice., PMID:40481552
Humoral and cellular immune responses in cattle upon Clostridium chauvoei vaccination and challenge., PMID:40463373
RNase 7 and Th cytokines synergistically increase the secretion of interleukin-6 from keratinocytes., PMID:40461723
Epithelial Regnase-1 inhibits colorectal tumor growth by regulating IL-17 signaling via degradation of NFKBIZ mRNA., PMID:40460118
IL-17A inhibitor-induced ulcerative colitis treated with an anti-IL-23 antibody., PMID:40455166
First successful treatment of epidermolytic Ichthyosis with Vunakizumab: A Case Report., PMID:40453098
[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135
Real-world safety assessment of Ixekizumab based on the FDA Adverse Event Reporting System (FAERS)., PMID:40408459
Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377
The MVA-VP2-NS1-2A-NS2-Nt vaccine candidate provides heterologous protection in sheep against bluetongue virus., PMID:40391210
Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis., PMID:40390069
Safety, pharmacokinetics, preliminary efficacy, pharmacodynamics, and immunogenicity of QX002N, an anti-IL-17A monoclonal antibody, after short-term treatment of active ankylosing spondylitis., PMID:40390042
Ixekizumab Retention Rate and Predictors of Treatment Persistence in Psoriatic Arthritis: Results of an Italian Multicenter Study., PMID:40376617
Crosstalk with infant-derived Th17 cells, as well as exposure to IL-22 promotes maturation of intestinal epithelial cells in an enteroid model., PMID:40375988
Biologic therapies and small molecules in the treatment of hidradenitis suppurativa., PMID:40373949
Extension of Secukinumab and Ixekizumab Dose for Moderate-To-Severe Psoriasis in Low Disease Activity Intervals., PMID:40369849
Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging., PMID:40366697
Gender Influence on Bimekizumab Response in Patients with Psoriasis: Results of a Real-World Multicenter Retrospective Study-IL PSO (Italian Landscape PSOriasis)., PMID:40358828
IL-17A, IL-17F, and IL-23 in Patients with Rheumatoid Arthritis., PMID:40353959
Chicken IL-17 as a potent adjuvant enhances IBDV VP2 DNA vaccine immunogenicity and protective efficacy., PMID:40347786
Treatment of severe psoriasis in a hospice care patient using secukinumab, an inhibitor of interleukin-17A expression: Treatment response and changes in quality of life., PMID:40329840
Secukinumab as a Novel Treatment for Chronic Netherton Syndrome in a Young Adult., PMID:40299794
Assessing the clinical progress of the bispecific nanobody sonelokimab., PMID:40297934
Inflammatory and Humoral Immune Responses to Commercial Autogenous Salmonella Bacterin Vaccines in Light-Brown Leghorn Pullets: Primary and Secondary Vaccine Responses., PMID:40266196
What are mice teaching us about psoriatic arthritis?, PMID:40265275
Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort., PMID:40264783
The novel antigen, lipopolysaccharide export protein LptH, protects mice against Pseudomonas aeruginosa acute pneumonia in monovalent and multivalent vaccines., PMID:40262371
Case Report: Spesolimab for pyoderma gangrenosum in an undifferentiated oligoarthritis patient receiving anti-IL-17 therapy., PMID:40260260
Targeting CD38 immunometabolic checkpoint improves metabolic fitness and cognition in a mouse model of Alzheimer's disease., PMID:40254603
Immune response in BALB/c mice to an attenuated strain of Nocardiabrasiliensis., PMID:40252937
Anti-integrin αvβ6 IgG antibody as a diagnostic and prognostic marker in ulcerative colitis: A cross-sectional and longitudinal study defining a specific disease phenotype., PMID:40251889
Sandwich-like electrochemical immunosensing of IL-17 based on silver nanoparticles/graphdiyne and methylene blue/UiO-66-NH2., PMID:40246749
Distinct immune memory induced by SARS-CoV-2 in convalescent liver transplant recipients., PMID:40242765
Real-World Experience of Bimekizumab in a Cohort of 109 Patients Over 48 Weeks and Identification of Predictive Factors for an Early Super Response and Risk of Adverse Events., PMID:40242569
[Mechanism of 2,6-DMBQ attenuates airway inflammatory responses in asthmatic mice via the mTOR signaling pathway]., PMID:40241367
OMIP-113: Characterization of Cytokine Producing T Cells in Swine., PMID:40231482
Unveiling the effectiveness and safety spectrum of biologic therapies in psoriasis: a three-year real-world analysis., PMID:40227059
Robust immune responses to intranasal vaccine targeting Bordetella pertussis antigens to claudin-4 on mucosal microfold cells., PMID:40220802
Expression Purification and Immunogenicity Detection of HtsA + FtsB Fusion Protein From Streptococcus pyogenes., PMID:40213873
Differential gut microbiota and inflammatory cytokines contribute to IgA vasculitis., PMID:40201970
Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety., PMID:40199321
Risk of De Novo Inflammatory Bowel Disease in Patients With Psoriasis and Psoriatic Arthritis Treated With IL-17A Inhibitors: A Population-Based Study., PMID:40192577