Catalog No.
VMC15801
Species reactivity
Mouse
Host species
Rat
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Interleukin HP-1, Il-6, Interleukin-6, B-cell hybridoma growth factor, IL-6, Il6
Concentration
1 mg/ml
Endotoxin level
< 1 EU/mg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, In vivo Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
MP5-20F3
Pro-dermcidin and derivatives as potential therapeutics for lethal experimental sepsis., PMID:40534887
Direct Interleukin-6 Inhibition Blunts Arterial Thrombosis by Reducing Collagen-Mediated Platelet Activation., PMID:40534557
Optimised nanobody-based quenchbodies for enhanced protein detection., PMID:40533519
Development of a novel system for the expression and production of recombinant monoclonal antibody, tocilizumab, using Pichia pastoris., PMID:40533031
Conserved domains of flagellin as adjuvants for an inactivated vaccine against porcine epidemic diarrhea virus., PMID:40532846
Immune response to and virological profile of SARS-CoV-2 before and after symptom onset in individuals vaccinated with inactivated COVID-19 vaccines., PMID:40530661
Inflammatory signatures and immunomodulation in neonates: a pilot study., PMID:40525368
Generation and Biological Characterization of an Anti-IL-6Rα Biosimilar Candidate Antibody., PMID:40524396
Pilot study of ABO-isogroup or universal plasma pools with or without pathogen reduction treatment., PMID:40522315
TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation., PMID:40512402
Role of Ocrelizumab in modulating gene and microRNA expression in multiple sclerosis., PMID:40510879
A Mixture of Free and Microencapsulated Essential Oils Combined with Turmeric and Tannin in the Diet of Dairy Cows: Effects on Productive Efficiency and Animal Health., PMID:40509055
Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies., PMID:40507880
FcRn inhibitors in immune thrombocytopenia: A comprehensive review of therapeutic advances and clinical outcomes., PMID:40505332
CTRP7 as a molecular biomarker associating with responsiveness to pulmonary vasodilators: insights from human and animal studies in pulmonary arterial hypertension., PMID:40504501
Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodies., PMID:40502578
Chronic administration of morphine provokes generation of antibodies to morphine and immunosuppression in individuals with opioid use disorder., PMID:40501089
Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903
A rare case report: acute necrotizing encephalopathy and acute fulminant myocarditis., PMID:40495992
Activin A exacerbates neonatal necrotizing enterocolitis via ALK4-mediated apoptosis and barrier disruption., PMID:40494204
The role of cytokines in pediatric hematologic malignancies: mechanisms of tumor progression and therapeutic implications - a narrative review., PMID:40486628
Novel pretransplant desensitization strategies in heart transplantation., PMID:40486117
[Correlation between soluble CD146 and systemic vasculitis]., PMID:40484821
The Use of Biologics for Thyroid Eye Disease., PMID:40478400
Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice., PMID:40464222
Glutamine and Isoleucine as the Key Amino Acids in Major IgE Linear Epitopes of α-Lactalbumin Identified by the Immune Peptide Microarray Assay For Chinese Bovine Milk Allergy., PMID:40462490
RNase 7 and Th cytokines synergistically increase the secretion of interleukin-6 from keratinocytes., PMID:40461723
IL-6: a pivotal molecule for tumor-brain dysfunction interaction., PMID:40461299
Dot-blot immunoassay based on antibody-nanocluster biohybrids as tags for naked-eye detection., PMID:40458008
Post-pandemic recommendations for the management of COVID-19 in patients with haematological malignancies or undergoing cellular therapy, from the European Conference on Infections in Leukaemia (ECIL-10)., PMID:40456838
Alternation of anti-NMDA receptor subunit GluN2 antibody in a patient with SLE who promptly developed anxiety after belimumab., PMID:40455606
Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294
The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313
Tocilizumab-Based Treatment of Microvascular Inflammation in Kidney Transplant Recipients: A Retrospective Study., PMID:40454296
Longitudinal analysis of cytokine dynamics in severe fever with thrombocytopenia syndrome patients - High-incidence regions of China (2010-2023)., PMID:40453472
A Spanish Porcine Reproductive and Respiratory Syndrome Virus 1 Strain Is Highly Virulent in Pigs Under Experimental Conditions., PMID:40453458
Multi-omics analysis reveals Angelica sinensis-Carthamus tinctorius herb pair ameliorates diabetic retinopathy comorbid with depressive symptoms via the gut-eye-brain axis., PMID:40449450
Immune responses and recovery from spotty liver disease in layer birds., PMID:40446677
The recombinant anti-MET/EpCAM bispecific antibody fragment: a promising novel therapeutic approach for breast cancer treatment., PMID:40445574
Soil-Transmitted Helminths and the Intricacies of Immunoregulation: Evidence From Amazonian Ecuador for the Importance of Considering Species-Specific Effects Within the Old Friends Hypothesis., PMID:40444920
Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712
Epstein-Barr virus infection increases the risk of depression: A cross-sectional study and Mendelian randomization analysis., PMID:40441653
Immunostimulatory effects of multiple short-hairpin RNAs enhance foot-and-mouth disease vaccine-induced humoral immunity., PMID:40441607
Antibody-mediated Rejection - Treatment Standard., PMID:40440205
Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming., PMID:40437667
IL-6 Inhibitors and TNF Inhibitors: Impact on Exercise-induced Cardiac Adaptations in Patients With Rheumatoid Arthritis., PMID:40436519
A case of Schnitzler syndrome complicated by rheumatoid arthritis treated with methotrexate., PMID:40433863
A Modular Mathematical Model of the Immune Response for Investigating the Pathogenesis of Infectious Diseases., PMID:40431602
OVA-Induced Food Allergy Leads to Neurobehavioral Changes in Mice and the Potential Role of Gut Microbiota and Metabolites Dysbiosis., PMID:40429903
C1q Binds to CD4+ T Cells and Inhibits the Release of Pro-Inflammatory Cytokines: Role in the Pathogenesis of Systemic Lupus Erythematosus., PMID:40429614