Catalog No.
VMC13501
Species reactivity
Mouse
Host species
Rat
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Il4, B-cell stimulatory factor 1, IL-4, BSF-1, B-cell growth factor 1, Interleukin-4, B-cell IgG differentiation factor, Lymphocyte stimulatory factor 1, IGG1 induction factor, Il-4
Concentration
1 mg/ml
Endotoxin level
< 1 EU/mg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, FCM, In vivo Neutralization, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
11B11
Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model., PMID:40529585
[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340
Decreased pathogenicity of triple-mutant of Aeromonas hydrophila flgK, flgL, flgE suggests its potential as a live attenuated vaccine for Carassius auratus., PMID:40516799
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat., PMID:40515672
A Promising Approach to Control Carbapenem-Resistant Acinetobacter baumannii: Investigating Immune Pathways Through rFilF Immunization., PMID:40513999
The dichotomous impacts of Semaphorin3E deficiency on exacerbating airway hyperresponsiveness, remodelling, and inflammation in type-2 low and type-2 high asthma models., PMID:40512736
Interleukin-4 and -13 Gene Expression Profiles in Immune-Related Bullous Pemphigoid Indicate Efficacy of IL-4/IL-13 Inhibitors., PMID:40507326
Improved protection against H9N2 avian influenza virus challenge in chickens by the presence of LTB adjuvant on the 3M2e-NP nanoparticle vaccine delivered by sifA deficient Salmonella., PMID:40505226
Dupilumab treatment has no effect on the nasal microbiome in patients with NSAID-exacerbated respiratory disease: a longitudinal pilot study., PMID:40503236
Baseline type 2 biomarker levels and clinical remission predictors in children with asthma., PMID:40503233
Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903
Selected cytokine and chemokine concentrations in equine autologous conditioned serum are similar under defined and practically relevant storage conditions., PMID:40496923
[Application and research progress of anti-IL-4α monoclonal antibody dupilumab in the treatment of type 2 asthma]., PMID:40491151
IL-18 favors Th2 responses in sporotrichosis caused by Sporothrix globosa, prolonging the course of the disease., PMID:40489556
Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710
Development of an oral gut-targeted rabies virus-like particles (RVLPs) vaccine with mucosal immune adjuvant LTB via delivering of localized-release microparticles., PMID:40476513
Protective Effect of Melissa officinalis (Lemon Balm) Extract on Cytokine Levels and Oxidative Stress in Ovalbumin Induced Lung Toxicity in Rats., PMID:40470741
Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients., PMID:40470156
Humoral and cellular immune responses in cattle upon Clostridium chauvoei vaccination and challenge., PMID:40463373
Suppression of Il5 and Il13 Gene Expression by Synthetic siRNA Molecules Reduces Nasal Hyperreactivity and Inflammation in a Murine Model of Allergic Rhinitis., PMID:40451198
Asthma therapeutics: Past, present, and future., PMID:40449124
Fusion with CTB enhances the immunogenicity and protective efficacy of MIC2 subunit vaccine against Eimeria tenella., PMID:40449102
Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice., PMID:40446078
Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712
How to Adjust Asthma Management Once Asthma Is Controlled on Long-Term Biologic Therapy., PMID:40436142
A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice., PMID:40432154
Long-Term Real-World Outcomes and Insights of Biologic Therapies in Chronic Rhinosinusitis with Nasal Polyps., PMID:40429838
PRRSV GP4 subunit vaccine combined with adenovirus heterologous prime-boost immunization strategy induced a significant immune response in mice., PMID:40426193
Antiallergic activities of polysaccharides derived from Coptis chinensis., PMID:40425117
Immunogenicity evaluation of a recombinant pseudorabies virus co-expressing PCV2 and PCV3 capsid proteins in mice and piglets., PMID:40424702
Cutaneous T Cell Lymphoma Following Dupilumab Therapy in Patients with Atopic Dermatitis: Clinical Review and Recommendations., PMID:40418285
[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135
The Combination of TLR4 and TLR9 Agonists with Self-Amplifying RNA Lipid Nanoparticles Leads to a More Powerful Immune Response Against SARS-CoV-2., PMID:40401447
Development of tolerogenic casein encapsulated quercetin and curcumin nanoparticles to mitigate cow milk allergic responses., PMID:40398766
Comparison of Different Methods of Constructing a Celiac Disease Model in BALB/c Mice., PMID:40395135
Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377
Acremonium terricola culture supplementation in the diet of pregnant and lactating Ewes can improve the production performance of Ewes and lambs by regulating maternal metabolism and antibody delivery., PMID:40389975
Lymphocyte Subsets in Covid-19 Saudi Patients: Infection Caused Significant Reduction in Peripheral Blood Lymphocyte Subset., PMID:40387754
Immune efficacy of oprH chitosan nanoparticle DNA vaccine against Pseudomonas aeruginosa., PMID:40386097
Expanding the potential of monoclonal antibodies against interleukin-4 and interleukin-13 in genodermatoses: A case series on the efficacy and safety of dupilumab in epidermolysis bullosa and ichthyosis., PMID:40386013
Immunogenicity Evaluation of a SARS-CoV-2 BA.2 Subunit Vaccine Formulated with CpG 1826 plus alum Dual Adjuvant., PMID:40383947
An oral recombinant human type 5 adenovirus vector vaccine encoding the S protein of Type I feline coronavirus effectively protection against FCoV challenge in cats., PMID:40381605
Exploring factors associated with clinical remission in patients with severe asthma receiving anti-IL-4Rα, anti-IL-5/5R, or anti-IgE treatment., PMID:40381526
Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection., PMID:40378045
Dupilumab for the Treatment of Cutaneous Immune-Related Adverse Events: A Systematic Review., PMID:40375468
Association of STAT6 gene polymorphism with atopic asthma among Yemeni children in Sana'a city, Yemen., PMID:40375219
Long-Term Longitudinal Analysis of Pulmonary Function Before and After Biological Therapy in Severe Asthma., PMID:40373751
T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting., PMID:40370530
Mycosis fungoides and IL-4/13 inhibitors: what is known and unmet needs., PMID:40369852
Сomprehensive approach to comparative characteristics of clinical and laboratory parameters of the study in children - in 6 months after Covid-19 treatment and 6 months after Covid-19 vaccination., PMID:40367469