Catalog No.
ELB93301
Expression system
Naturally Extracted.
Species
Human
Protein length
Full length.
Predicted molecular weight
660 kDa
Nature
Recombinant
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01266
Applications
ELISA, Immunogen, SDS-PAGE, WB
Form
Liquid
Storage buffer
Liquid from 20 mM PBS pH7.4.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Thyroglobulin, Tg, TG
Disruption of LDL receptor trafficking in placentas from maternal supraphysiological hypercholesterolemia: A study of key endocytosis and recycling proteins., PMID:40517484
TAGLN2 Exacerbates Acute Pancreatitis-Induced Liver Injury by Increasing Hepatocyte Pyroptosis via Kupffer Cells-Mediated Inflammatory Response., PMID:40472315
Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity., PMID:40407837
Genetic Etiology of Permanent Congenital Hypothyroidism in Korean Patients: A Whole-Exome Sequencing Study., PMID:40362701
TAGLN2-mediated Actin Cytoskeleton Stabilization Promotes Proliferation and Metastasis of Ovarian Carcinoma., PMID:40247723
Restoration of Transgelin 2 Expression Reverses Immune Escape in Ovarian Cancer: A Dawn for Immunotherapy., PMID:40166645
SDC4 drives fibrotic remodeling of the intervertebral disc under altered spinal loading., PMID:40161806
Multi-Omic Insight Into the Molecular Networks in the Pathogenesis of Coronary Artery Disease., PMID:40135555
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen., PMID:40119106
Multifaceted role of transgelin isoforms in cancer hallmarks., PMID:40102702
Trimethylamine-N-oxide affects cell type-specific pathways and networks in mouse aorta to promote atherosclerotic plaque vulnerability., PMID:40060573
Single Cell Proteomics Reveals Novel Cell Phenotypes in Marfan Mouse Aneurysm., PMID:40027651
RhoA/ROCK/GSK3β Signaling: A Keystone in Understanding Alzheimer's Disease., PMID:39996845
Measurements of Iodination in Thyroglobulin: A Step Toward the Next Generation of Thyroid Cancer Monitoring., PMID:39911521
The Ubiquitin Ligase CHIP Accelerates Papillary Thyroid Carcinoma Metastasis via the Transgelin-Matrix Metalloproteinase-9 Axis., PMID:39869438
eIF4A1 exacerbates myocardial ischemia-reperfusion injury in mice by promoting nuclear translocation of transgelin/p53., PMID:39856433
The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist., PMID:39845780
Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series., PMID:39836188
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis., PMID:39781462
The Oxidoreductase Retinol Saturase in Thyroid Gland Is Regulated by Hypothyroidism and Iodide Overload and Its Deletion Impairs Metabolic Homeostasis in Mice., PMID:39761014
Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries., PMID:39729736
A xenogenic-free culture medium for cell micro-patterning systems as cell-instructive biomaterials for potential clinical applications., PMID:39719129
Serum transgelin is a novel prognostic biomarker for COVID-19 patients., PMID:39676863
Sphingosine 1-phosphate acts as proliferative and fibrotic cue in leiomyoma cells., PMID:39643001
Down-regulation of TAGLN2 associated with the development of preeclampsia by effecting the Rap1 signaling pathway., PMID:39602835
Novel Gene Biomarkers Specific to Human Mesenchymal Stem Cells Isolated from Bone Marrow., PMID:39595975
HIF-1α knockdown attenuates phenotypic transformation and oxidative stress induced by high salt in human aortic vascular smooth muscle cells., PMID:39543255
MALDI MSI Protocol for Spatial Bottom-Up Proteomics at Single-Cell Resolution., PMID:39447324
Transgelin 2 guards T cell lipid metabolism and antitumour function., PMID:39443795
Identifying clinical and proteomic markers for early diagnosis and prognosis prediction of major psychiatric disorders., PMID:39426510
Functional heterogeneity of meniscal fibrochondrocytes and microtissue models is dependent on modality of fibrochondrocyte isolation., PMID:39377189
Unveiling the role of transgelin as a prognostic and therapeutic target in kidney fibrosis via a proteomic approach., PMID:39375532
Expression of thyroid antigens in the female reproductive system., PMID:39373190
Development and primary characterization of a human thyroid organoid in vitro model for thyroid metabolism investigation., PMID:39343290
Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers., PMID:39335130
Correction: Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery., PMID:39316381
Molecular biomarkers involved in the progression of gallbladder inflammatory lesions to invasive cancer: A proteomic approach., PMID:39284282
Preclinical pharmacokinetic studies and prediction of human PK profiles for Deg-AZM, a clinical-stage new transgelin agonist., PMID:39253379
Clinical and molecular study of patients with thyroid dyshormogenesis and variants in the thyroglobulin gene., PMID:39040671
Clinical efficacy of multigene panels in the management of congenital hypothyroidism with gland in situ., PMID:39029043
Genetic etiology in patients diagnosed with congenital hypothyroidism with new-generation sequencing: A single-center experience., PMID:39003160
TGFβ1 Regulates Cellular Composition of In Vitro Cardiac Perivascular Niche Based on Cardiospheres., PMID:38963596
Cyclosporine A Protects Podocytes by Regulating Transgelin in Adriamycin-Induced Podocyte Injury., PMID:38952124
Identification of southern Taiwan genetic variants in thyroid dyshormonogenesis through whole-exome sequencing., PMID:38923290
Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries., PMID:38915529
Basal ATP release signals through the P2Y2 receptor to maintain the differentiated phenotype of vascular smooth muscle cells., PMID:38889566
CD163+ Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma., PMID:38860377
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells., PMID:38744388
Urinary Insulin-Like Growth Factor-Binding Protein 7 (IGFBp7), Urinary Tissue Inhibitor of Matrix Metalloproteinase 2 (TIMP2), and Serum Transgelin as Novel Biomarkers of Kidney Injury in Multiple Myeloma., PMID:38708150
KLF13 promotes VSMCs phenotypic dedifferentiation by directly binding to the SM22α promoter., PMID:38634445