Catalog No.
YVV14707
Expression system
E. coli
Species
Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus)
Protein length
Met1-Cys168
Predicted molecular weight
21.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19711
Applications
ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
N-terminal protease, Autoprotease p20, Npro
Exogenous interactome analysis of bovine viral diarrhea virus-host using network based-approach and identification of hub genes and important pathways involved in virus pathogenesis., PMID:39318471
The host protein CALCOCO2 interacts with bovine viral diarrhoea virus Npro, inhibiting type I interferon production and thereby promoting viral replication., PMID:38047736
Immunoinformatic prediction of the pathogenicity of bovine viral diarrhea virus genotypes: implications for viral virulence determinants, designing novel diagnostic assays and vaccines development., PMID:37483297
Pestiviruses infection: Interferon-virus mutual regulation., PMID:36936761
Isolation of BVDV-1a, 1m, and 1v strains from diarrheal calf in china and identification of its genome sequence and cattle virulence., PMID:36467650
Non-structural proteins of bovine viral diarrhea virus., PMID:35614328
Fifty Shades of Erns: Innate Immune Evasion by the Viral Endonucleases of All Pestivirus Species., PMID:35215858
Bungowannah Pestivirus Chimeras as Novel Double Marker Vaccine Strategy against Bovine Viral Diarrhea Virus., PMID:35062749
Positively Charged Amino Acids in the Pestiviral Erns Control Cell Entry, Endoribonuclease Activity and Innate Immune Evasion., PMID:34452446
Cattle connection: molecular epidemiology of BVDV outbreaks via rapid nanopore whole-genome sequencing of clinical samples., PMID:34247601
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production., PMID:34097933
Novel Potent IFN-γ-Inducing CD8+ T Cell Epitopes Conserved among Diverse Bovine Viral Diarrhea Virus Strains., PMID:33762324
Guinea pig cytomegalovirus protective T cell antigen GP83 is a functional pp65 homolog for innate immune evasion and pentamer dependent virus tropism., PMID:33658350
A Synthetic Modified Live Chimeric Marker Vaccine against BVDV-1 and BVDV-2., PMID:33023099
An extensive field study reveals the circulation of new genetic variants of subtype 1a of bovine viral diarrhea virus in Uruguay., PMID:31745717
Experimental infection of Korean native goats (Capra aegagrus hircus) with bovine viral diarrhea virus 1b., PMID:31200717
Who's who in the Bovine viral diarrhea virus type 1 species: Genotypes L and R., PMID:30056173
BVDV Npro protein mediates the BVDV induced immunosuppression through interaction with cellular S100A9 protein., PMID:29859294
The Occurrence of a Commercial Npro and Erns Double Mutant BVDV-1 Live-Vaccine Strain in Newborn Calves., PMID:29783722
Npro His49 and Erns Lys412 mutations in pig bovine viral diarrhea virus type 2 synergistically enhance the cellular antiviral response., PMID:28852929
Type 2 BVDV Npro suppresses IFN-1 pathway signaling in bovine cells and augments BRSV replication., PMID:28432927
Pig BVDV-2 non-structural protein (Npro) links to cellular antiviral response in vitro., PMID:27866318
What can pestiviral endonucleases teach us about innate immunotolerance?, PMID:27021825
Identification and molecular characterization of border disease virus (BDV) from sheep in India., PMID:26851587
Molecular diversity of bovine viral diarrhea virus in uruguay., PMID:26597189
Prevalence study and genetic typing of bovine viral diarrhea virus (BVDV) in four bovine species in China., PMID:25849315
Development of sheep kidney cells with increased resistance to different subgenotypes of BVDV-1 by RNA interference., PMID:25813600
Analysis of a pair of END+ and END- viruses derived from the same bovine viral diarrhea virus stock reveals the amino acid determinants in Npro responsible for inhibition of type I interferon production., PMID:25648277
Increased genetic diversity of BVDV-1: recent findings and implications thereof., PMID:25349062
Insertion and stable expression of Gaussia luciferase gene by the genome of bovine viral diarrhea virus., PMID:25108838
Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex., PMID:24965446
Stability of the resistance to the thiosemicarbazone derived from 5,6-dimethoxy-1-indanone, a non-nucleoside polymerase inhibitor of bovine viral diarrhea virus., PMID:24950191
Clinical Presentation Resembling Mucosal Disease Associated with 'HoBi'-like Pestivirus in a Field Outbreak., PMID:24735072
The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.)., PMID:24551175
Molecular investigation of bovine viral diarrhea virus infection in yaks (Bos gruniens) from Qinghai, China., PMID:24524442
N pro of Bungowannah virus exhibits the same antagonistic function in the IFN induction pathway than that of other classical pestiviruses., PMID:24398226
Characterization of a bovine viral diarrhea virus originated from cattle in Gansu Province, China., PMID:23681710
BVDV: a pestivirus inducing tolerance of the innate immune response., PMID:22871358
Comparative [corrected] codon usage between the three main viruses in pestivirus genus and their natural susceptible livestock., PMID:22395914
An alternative -1/+2 open reading frame exists within viral N(pro)(1-19) region of bovine viral diarrhea virus SD-1., PMID:22079882
TRIM56 is a virus- and interferon-inducible E3 ubiquitin ligase that restricts pestivirus infection., PMID:21289118
Genetic and antigenic characterization of bovine viral diarrhoea virus type 2 isolated from cattle in India., PMID:21112633
Genetic and antigenic typing of border disease virus (BDV) isolates from Italy reveals the existence of a novel BDV group., PMID:20656426
Evidence of a humoral immune response against the prokaryotic expressed N-terminal autoprotease (N(pro)) protein of bovine viral diarrhoea virus., PMID:20413912
Novel BVDV-2 mutants as new candidates for modified-live vaccines., PMID:19875253
Characterisation of a new infectious full-length cDNA clone of BVDV genotype 2 and generation of virus mutants., PMID:19875251
Effect of the viral protein N(pro) on virulence of bovine viral diarrhea virus and induction of interferon type I in calves., PMID:19719427
Phylogeny, classification and evolutionary insights into pestiviruses., PMID:19167739
Genotyping and phylogenetic analysis of bovine viral diarrhea virus isolates from BVDV infected alpacas in North America., PMID:19059738
Genetic analysis of a bovine viral diarrhea virus 2 isolate from Slovakia., PMID:18999890
For research use only. Not for human or drug use.
