Catalog No.
AMC06703
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Ala18-Lys141
Predicted molecular weight
15.1 kDa
Nature
Recombinant
Endotoxin level
< 1 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
P01587
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Granulocyte-Macrophage Colony-Stimulating Factor, GM-CSF, Colony-Stimulating Factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF
Colony-stimulating factor 2 (CSF2) does not significantly affect cellular and molecular parameters, or blastocyst rates under in vitro culture conditions with reduced nutrient concentrations., PMID:40334542
Identification of BHLHE40-Expressing CD4+ T Cells Producing GM-CSF in Rheumatoid Arthritis., PMID:40223427
Seminal Fluid Interaction with Female Reproductive Tract Epithelial Cells: In Vitro Models for Human., PMID:40202668
CSF2 promotes chemoresistance in colorectal cancer by regulating Notch pathway., PMID:40202620
Respiratory symptoms, sensitisation and occupational exposure in the shrimp processing industry., PMID:40181810
CircPRKCA facilitates esophageal squamous cell carcinoma metastasis via m5C-dependent CSF2 mRNA stabilization., PMID:40170133
Modulation of Macrophages TLR4-Mediated Transcriptional Response by Lacticaseibacillus rhamnosus CRL1505 and Lactiplantibacillus plantarum CRL1506., PMID:40141330
The role of osteopontin in modulating macrophage phagocytosis of calcium oxalate crystals., PMID:40131428
In vitro and in vivo characterization of oridonin analogs as anti-inflammatory agents that regulate the NF-κB and NLRP3 inflammasome axis., PMID:40083382
Lower expression of colony-stimulating factor 2, an embryokine, in the endometrial epithelium of old cows., PMID:39951370
Activation of the tumor cell-intrinsic STING pathway induced by Fusobacterium nucleatum is associated with poor prognosis in esophageal cancer patients., PMID:39951185
Dimethyl Fumarate attenuates synovial inflammation, reduces nociception, and inhibits the development of post-traumatic osteoarthritis., PMID:39862703
Menin orchestrates macrophage reprogramming to maintain the pulmonary immune homeostasis., PMID:39817905
Inflammatory Response of THP1 and U937 Cells: The RNAseq Approach., PMID:39768153
Unlocking the Therapeutic Potential of Adipose-Derived Stem Cell Secretome in Oral and Maxillofacial Medicine: A Composition-Based Perspective., PMID:39765683
Knockdown of HOXD13 in Oral Squamous Cell Carcinoma Inhibited its Proliferation, Migration, and Influenced Fatty Acid Metabolism., PMID:39744569
Pulmonary exposure to renewable diesel exhaust particles alters protein expression and toxicity profiles in bronchoalveolar lavage fluid and plasma of mice., PMID:39739031
Comprehensive analysis of differentially expressed genes in toll-like receptor signalling pathway: Insights into new-onset microscopic polyangiitis., PMID:39672520
ILC1 as critical gatekeepers in autoimmune kidney damage., PMID:39642908
Mesenchymal stem cells treated with Interleukin-1 beta for mediation of an inflammatory response in human tissues., PMID:39605126
Regulatory Effect of Fucoidan Hydrolysates on Lipopolysaccharide-Induced Inflammation and Intestinal Barrier Dysfunction in Caco-2 and RAW264.7 Cells Co-Cultures., PMID:39593947
Characterising the transcriptomic response of bovine peripheral blood mononuclear cells to a mycobacterial cell wall fraction., PMID:39566357
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors., PMID:39551979
Visualizing the spatial organization of monocytes, interstitial macrophages, and tissue-specific macrophages in situ., PMID:39395172
Methotrexate promotes the release of granulocyte-macrophage colony-stimulating factor from rheumatoid arthritis fibroblast-like synoviocytes via autocrine interleukin-1 signaling., PMID:39394168
Anti-tumor potential of high salt in breast Cancer cell lines., PMID:39305332
In vitro biomaterial priming of human mesenchymal stromal/stem cells : implication of the Src/JAK/STAT3 pathway in vasculogenic mimicry., PMID:39271790
In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue., PMID:39263317
Elevated hydrostatic pressure disturbs expression of growth factors in human renal epithelial cells., PMID:39240898
Amplification of autoimmune organ damage by NKp46-activated ILC1s., PMID:39137897
Colony-stimulating factor 2 (CSF2) as a gut microbiome dependent immune factor that alters molecular and behavioral responses to cocaine in male mice., PMID:39098439
Inflammation-Related Gene ADH1A Regulates the Polarization of Macrophage M1 and Influences the Malignant Progression of Gastric Cancer., PMID:39045532
Cancer-associated fibroblast-derived colony-stimulating factor 2 confers acquired osimertinib resistance in lung adenocarcinoma via promoting ribosome biosynthesis., PMID:39036343
Analysis of alpha-1-antitrypsin (AAT)-regulated, glucocorticoid receptor-dependent genes in macrophages reveals a novel host defense function of AAT., PMID:39016119
PAR2 activation on human tubular epithelial cells engages converging signaling pathways to induce an inflammatory and fibrotic milieu., PMID:39005931
Mechanism of Lian Hua Qing Wen capsules regulates the inflammatory response caused by M1 macrophage based on cellular experiments and computer simulations., PMID:39002739
Comparing machine learning screening approaches using clinical data and cytokine profiles for COVID-19 in resource-limited and resource-abundant settings., PMID:38937503
Therapeutic targets for age-related macular degeneration: proteome-wide Mendelian randomization and colocalization analyses., PMID:38903171
Disrupting Smad3 potentiates immunostimulatory function of NK cells against lung carcinoma by promoting GM-CSF production., PMID:38878186
The potential mechanism of WT1-associated protein-induced N-6-methyladenosine modification of colony-stimulating factor 2 in the progression of oral squamous cell carcinoma by JAK/STAT3 pathway regulation., PMID:38831514
The mechanism of multistep progression of the transcriptional cascade in activated microglia as approached by a proteome approach., PMID:38824862
Liquiritin Alleviates Inflammation in Lipopolysaccharide-Induced Human Corneal Epithelial Cells., PMID:38767463
Anticancer Potential of Postbiotic Derived from Lactobacillus brevis and Lactobacillus casei: In vitro Analysis of Breast Cancer Cell Line., PMID:38758482
Bound polyphenols in insoluble dietary fiber of navel orange peel modulate LPS-induced intestinal-like co-culture inflammation through CSF2-mediated NF-κB/JAK-STAT pathway., PMID:38738974
The Recombinant Oncolytic Virus VV-GMCSF-Lact and Chemotherapy Drugs against Human Glioma., PMID:38673835
A GITRL-mTORC1-GM-CSF Positive Loop Promotes Pathogenic Th17 Response in Primary Sjögren Syndrome., PMID:38589318
Rheumatoid arthritis synovial fluid shows enrichment of T-cells producing GMCSF which are polyfunctional for TNFα and IFNγ., PMID:38372731
Identification of a novel glioblastoma multiforme molecular subtype with poor prognosis and high immune infiltration based on oxidative stress-related genes., PMID:38363895
Whole Blood Transcriptome Analysis in Patients with Trigeminal Neuralgia: a Prospective Clinical Study., PMID:38300339
[Ferroptosis inducer IKE ameliorate pulmonary fibrosis in collagen-induced arthritis (CIA) mice via decreasing the expression of IL-6, CCL5 and CXCL9]., PMID:38284252
For research use only. Not for human or drug use.
