Catalog No.
AHB41601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Glu28-Ala207
Predicted molecular weight
21.9kDa
Nature
Recombinant
Endotoxin level
< 0.01 EU/µg as determined by LAL test.
Purity
>90% as determined by SDS-PAGE.
Accession
O76093
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibroblast growth factor 18, FGF-18, FGF18, zFGF5
Peptide-based smart nanosystem for spatiotemporal regulation of bone immunity and cartilage repair to alleviate osteoarthritis., PMID:40449082
Fibroblast growth factor 18 attenuates renal fibrosis via AMPK/NOX4 pathway in mice., PMID:40311293
FGF18 induces chondrogenesis and anti-osteoarthritic effects in a mouse model for TMJ degeneration., PMID:40273050
Transcriptome Analysis Reveals Anti-inflammatory, Antiapoptotic, and Milk Synthesis-Promoting Effects of Lithium Chloride in Bovine Mammary Epithelial Cells., PMID:40214951
Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson's disease., PMID:40071608
KLF5 enhances CXCL12 transcription in adipose-derived stem cells to promote endothelial progenitor cells neovascularization and accelerate diabetic wound healing., PMID:40038579
Refining of cancer-specific genes in microsatellite-unstable colon and endometrial cancers using modified partial least square discriminant analysis., PMID:39969322
Assessing serum and biopsy biomarkers for predicting allergic asthma severity: a comprehensive study., PMID:39932249
High FGF18 expression levels predict poor prognosis in endometrial carcinoma patients and promote tumor growth and metastasis., PMID:39852234
3D bio-printed proteinaceous bioactive scaffold loaded with dual growth factor enhanced chondrogenesis and in situ cartilage regeneration., PMID:39845130
Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence., PMID:39844298
Transcriptome integration analysis revealed that miR-103-3p regulates goat myoblast proliferation by targeting FGF18., PMID:39773020
Injectable Fibrocartilage-Forming Cores Enhance Bone-Tendon Healing in a Rat Rotator Cuff Model., PMID:39741471
MicroRNA expression profiles in plasma exosomes of late pregnant giant pandas., PMID:39422788
Comprehensive in silico analysis of prognostic and immune infiltrates for FGFs in human ovarian cancer., PMID:39385288
HIF-1α induced FGF18 alleviates renal ischemia/reperfusion injury via YAP., PMID:39373977
Targeted Therapy of Osteoarthritis via Intra-Articular Delivery of Lipid-Nanoparticle-Encapsulated Recombinant Human FGF18 mRNA., PMID:39363784
Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth., PMID:39304765
WYC-209 suppresses gastric cancer by down-regulating FGF18 via inactivating the STAT3 signaling pathway., PMID:39214271
RNAseq of Gingival Fibroblasts Exposed to PRF Membrane Lysates and PRF Serum., PMID:39120336
FGF18 encoding circular mRNA-LNP based on glycerolipid engineering of mesenchymal stem cells for efficient amelioration of osteoarthritis., PMID:39037353
BUB1 potentiates gastric cancer proliferation and metastasis by activating TRAF6/NF-κB/FGF18 through m6A modification., PMID:39025206
Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family., PMID:38902808
Is detection of disease-modifying osteoarthritis drug treatment more effective when performing cartilage morphometry without blinding to MR image acquisition order?, PMID:38844160
Interplay of clinical biomarkers in allergic asthma diagnosis and severity: A case-control study., PMID:38814233
FGF18 impairs blastocyst viability, DNA double-strand breaks and maternal recognition of pregnancy genes., PMID:38796960
Single Injection AAV2-FGF18 Gene Therapy Reduces Cartilage Loss and Subchondral Bone Damage in a Mechanically Induced Model of Osteoarthritis., PMID:38783531
A comparative study of multiple biomarkers levels in complicated versus noncomplicated type 2 diabetic patients., PMID:38678628
Prognostic gene biomarkers for c-Src inhibitor Si162 sensitivity in melanoma cells., PMID:38665777
FGF18 alleviates sepsis-induced acute lung injury by inhibiting the NF-κB pathway., PMID:38419044
A Bionic Thermosensitive Sustainable Delivery System for Reversing the Progression of Osteoarthritis by Remodeling the Joint Homeostasis., PMID:38394066
Effect and mechanism of recombinant human fibroblast growth factor 18 on osteoporosis in OVX mice., PMID:38275172
Injectable Microgels with Hybrid Exosomes of Chondrocyte-Targeted FGF18 Gene-Editing and Self-Renewable Lubrication for Osteoarthritis Therapy., PMID:38266145
Fibroblast growth factor signalling regulates the development of tooth root., PMID:38258312
Ginsenosides in Panax ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation., PMID:38246611
MYH1G-AS is a chromatin-associated lncRNA that regulates skeletal muscle development in chicken., PMID:38177995
FGFs function in regulating myoblasts differentiation in spotted sea bass (Lateolabrax maculatus)., PMID:38103843
Sympathetic Neurotransmitter, VIP, Delays Intervertebral Disc Degeneration via FGF18/FGFR2-Mediated Activation of Akt Signaling Pathway., PMID:38047500
FGF18., PMID:38007374
Computer-assisted stabilization of fibroblast growth factor FGF-18., PMID:37920818
Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis., PMID:37907525
FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway in male mice., PMID:37777507
The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy., PMID:37664846
Pan-cancer Analysis Reveals Cancer-dependent Expression of SOX17 and Associated Clinical Outcomes., PMID:37643784
CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications., PMID:37640697
FGF-18 Protects the Injured Spinal cord in mice by Suppressing Pyroptosis and Promoting Autophagy via the AKT-mTOR-TRPML1 axis., PMID:37581847
Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel FGFR4 inhibitors for the treatment of colorectal cancer., PMID:37556948
Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization., PMID:37529250
FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer's disease., PMID:37506425
A high-sensitivity ELISA for detection of human FGF18 in culture supernatants from tumor cell lines., PMID:37453260
For research use only. Not for human or drug use.
