Catalog No.
YHH35001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp374-Phe516
Predicted molecular weight
18.4 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16678
Applications
ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CYPIB1, Cytochrome P450 1B1, Hydroperoxy icosatetraenoate dehydratase, CYP1B1
Kynurenine enhances aryl hydrocarbon receptor signaling and expression levels of multidrug resistance genes in head and neck squamous cell carcinoma cell lines but does not change the potency of antineoplastic drugs., PMID:40532857
Protein-level analysis of differential response to chemotherapy in triple negative breast cancer identifies CYP1B1 as a biomarker for chemotherapy resistance., PMID:40478625
Potential of Indole-3-Carbinol compounds from broccoli (Brassica oleracea var. italica) as natural aromatase blockers: In silico prediction and in vivo studies., PMID:40453864
CYP1B1 promotes angiogenesis and sunitinib resistance in clear cell renal cell carcinoma via USP5-mediated HIF2α deubiquitination., PMID:40435846
Identification of potential key targets and mechanisms underlying cleft palate induced by tobacco smoke exposure through multi-omics integrated Mendelian randomization analysis., PMID:40435780
Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line., PMID:40412367
Transcriptomic profiling provide insights into swainsonine-induced toxic responses and activation of the aryl hydrocarbon receptor pathway., PMID:40381828
Comparison of submerged and air liquid interface exposure: limitations and differences in the toxicological effects evaluated in bronchial epithelial cells., PMID:40379004
The importance of CYP1B1 polymorphism in obesity., PMID:40355228
Combination of RNA-sequencing data analysis, network pharmacology, molecular docking techniques to investigate the mechanism of Prunella vulgaris L. in the treatment of non-small cell lung cancer., PMID:40353950
Effect of MiRNA 204-5P Mimics and Lipopolysaccharide-Induced Inflammation on Transcription Factor Levels, Cell Maintenance, and Retinoic Acid Signaling in Primary Limbal Epithelial Cells., PMID:40332443
Effects of an aryl hydrocarbon receptor ligand on human trophoblast cell development., PMID:40294436
Sex-dependent alterations in cardiac cytochrome P450-mediated arachidonic acid metabolism in pressure overload-induced cardiac hypertrophy in rats., PMID:40273825
Identification of Anoikis-Related Genes in Gastric Cancer: Bioinformatics and Experimental Validation., PMID:40263929
Unraveling the mechanisms of Shaoyang Shenggu decoction in treating knee osteoarthritis through mass spectrometry and bioinformatics., PMID:40258527
Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates., PMID:40258480
Exploring the role of gut microbiota modulation in the long-term therapeutic benefits of early MSC transplantation in MRL/lpr mice., PMID:40251524
LncRNA CYP1B1-AS1 as a clinical biomarker exacerbates sepsis inflammatory response via targeting miR- 18a- 5p., PMID:40234801
Pathogenic variants identification in primary congenital glaucoma patients using whole exome sequencing., PMID:40169658
Insight into the Role of the Aryl Hydrocarbon Receptor in Bovine Coronavirus Infection by an Integrated Approach Combining In Vitro and In Silico Methods., PMID:40142473
Microglial NOX2 as a therapeutic target in traumatic brain injury: Mechanisms, consequences, and potential for neuroprotection., PMID:40122395
Amino Acid Stress Response Genes Contribute to a 25-Fold Increased Risk of L-Asparaginase-Induced Hypersensitivity., PMID:40119746
Defined Diets Link Iron and α-Linolenic Acid to Cyp1b1 Regulation of Neonatal Liver Development Through Srebp Forms and LncRNA H19., PMID:40076634
Effects of combined stressors to TCDD and high temperature on HSP/CYPs signaling in the zebrafish embryos/larvae., PMID:40073960
Farnesoid X receptor regulates CYP1A1 and CYP1B1 and estradiol metabolism in mouse and human cell lines., PMID:40064219
B7-H3-mediated deubiquitination stabilizing CYP1B1 expression promotes chemotherapy resistance in colorectal cancer., PMID:40057208
Heme-thiolate monooxygenase cytochrome P450 1B1, an old dog with many new tricks., PMID:40054133
Association of Inherited Genetic Variants with Multiple Primary Melanoma., PMID:40036058
KLF9, Epigenetic Silenced by DNMT1, Promotes ERK-Mediated Ferroptosis of Osteoarthritic Chondrocytes Through Transcriptionally Regulating CYP1B1., PMID:40016915
Identification and structural analysis of pathogenic variants in MYOC and CYP1B1 genes in Indian JOAG patients., PMID:39998747
Analysis of early-onset glaucoma genes in primary congenital glaucoma patients residing in North India identifies an additional case with THBS1 Arg1034Cys., PMID:39995314
Estrogen and Cyp1b1 Regulate Pparγ in Pulmonary Hypertension Through a Ubiquitin-Dependent Mechanism., PMID:39958970
Molecular Docking Study and 3D-QSAR Model for Trans-Stilbene Derivatives as Ligands of CYP1B1., PMID:39940769
Central Interaction of 2-Methoxyestradiol and Lipoxygenase in AngII-Hypertension., PMID:39902602
Investigating the sexual dimorphism in isoproterenol-induced cardiac hypertrophy in Sprague Dawley rats., PMID:39891968
Zebrafish Cyp1b1 knockout alters eye and brain metabolomic profiles, affecting ocular and neurobehavioral function., PMID:39890032
Application of a CYP1B1-Targeted NIR Probe for Breast Cancer Diagnosis, Surgical Navigation, and CYP1B1-Associated Chemotherapy Resistance Monitoring., PMID:39885683
Pinocembrin alleviates renal ischemia-reperfusion injury/unilateral ureteral obstruction (UUO)-generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axis., PMID:39876048
Auxin Triggers AHR Pathway Activation in the Auxin-Inducible Degron System in Mammalian Cells., PMID:39865034
Characterization of Five Natural Anthraquinone Compounds as Potent Inhibitors against CYP1B1: Implications for Cancer Treatment., PMID:39838665
Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1., PMID:39806854
Tryptophan metabolism-related gene CYP1B1 serves as a shared biomarker for both Parkinson's disease and insomnia., PMID:39779759
Impact of Long-Term Cannabidiol (CBD) Treatment on Mouse Kidney Transcriptome., PMID:39766907
[Precision Medicine for Patients with Renal Cell Carcinoma Based on Drug-metabolizing Enzyme Expression Levels]., PMID:39756928
Dioxin-like effects of an emerging contaminant 1,3,6,8-tetrabromocarbazole on the myogenic differentiation of mouse C2C12 cells., PMID:39756783
Identification and validation of Novel Estrogen Biosynthesis Biomarkers in Sinonasal Inverted Papilloma., PMID:39744163
Exposure to Bisphenol A jeopardizes decidualization and consequently triggers preeclampsia by up-regulating CYP1B1., PMID:39740546
Unveiling the substantial role of rutin in the management of drug-induced nephropathy using network pharmacology and molecular docking., PMID:39733639
Oxidative stress promotes lipid-laden macrophage formation via CYP1B1., PMID:39721495
Functional genomics of primary congenital glaucoma by pathway analysis and functional characterization of CYP1B1 mutations., PMID:39721180
For research use only. Not for human or drug use.
