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Recombinant Mouse RUNX2 Protein, N-His

Catalog #:   YMG67902 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q08775
Protein length: Pro422-Arg554
Overview

Catalog No.

YMG67902

Expression system

E. coli

Species

Mus musculus (Mouse)

Protein length

Pro422-Arg554

Predicted molecular weight

23.78 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q08775

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

AML3, OSF2, RUNX2, Core-binding factor subunit alpha-1, PEA2-alpha A, CBF-alpha-1, Osteoblast-specific transcription factor 2, Oncogene AML-3, CBFA1, Runt-related transcription factor 2, PEBP2A, OSF-2, SL3-3 enhancer factor 1 alpha A subunit, PEBP2-alpha A, Acute myeloid leukemia 3 protein, Polyomavirus enhancer-binding protein 2 alpha A subunit, SL3/AKV core-binding factor alpha A subunit

Data Image
References

Neodymium-modified Mg-Zn-Zr magnesium alloy as a biodegradable osteogenic implant., PMID:40530420

Chemical composition and nutritional properties of Gastrodia elata water extract and its effects in rats with streptozotocin-induced diabetic osteoporosis., PMID:40529421

Osteoinductivity performance dicalcium phosphate dihydrate-coated porous β-tricalcium phosphate granules in adipose-derived mesenchymal stem cells., PMID:40518314

Klotho promotes bone formation in rheumatoid arthritis-associated osteoporosis by modulating the Fgf23/Fgfr1/NF-κB pathway and inhibiting ferroptosis., PMID:40513341

Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes., PMID:40507779

RUNX2 isoform II protects cancer cells from ferroptosis and apoptosis by promoting PRDX2 expression in oral squamous cell carcinoma., PMID:40498062

Gold-doped wollastonite nanohybrids enhance bone regeneration via the bone morphogenetic protein-2, SMAD1, and Runt-related transcription factor-2 signalling pathway., PMID:40487310

Jatrorrhizine Alleviates Calcific Aortic Valve Disease via Interfering With Glycolysis Targeting ALDOA K42 Lactylation., PMID:40485074

CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p., PMID:40481048

LncRNA CA13/EFTUD2/CA13 caused crossed beak by regulating the mandibular calcification in chicken., PMID:40480132

Activation of GLP-1 receptors enhances the osteogenic differentiation process of STRO-1-positive BMSCs., PMID:40478323

Knockout of the Staphylococcus aureus virulence gene sdrC promotes Myh7 expression to inhibit the progression of osteomyelitis., PMID:40471432

A comparative study of three liquid platelet concentrates on human primary osteoblast activity: an in vitro study., PMID:40465952

Expression of Osteogenic Genes in Dental Pulp and Their Correlations in Patients with Clinically Diagnosed Irreversible Pulpitis., PMID:40464527

Engineered BMP2/BMP7 extracellular vesicles induce autocrine BMP release driving SMAD phosphorylation to promote bone formation., PMID:40461558

Porphyromonas gingivalis induced DNA oxidative stress damage by iron overload to deplete CTCF expression and prevent osteogenic differentiation of periodontal ligament stem cells., PMID:40455363

Isorhamnetin ameliorates ovariectomy-induced osteoporosis in female rats by regulating the receptor activator of nuclear factor kappa B ligand, osteoprotegerin, bone morphogenetic protein 2 and runt-related transcription factor 2 signaling pathway., PMID:40451839

FTVI promotes osteogenic differentiation of bone marrow mesenchymal stem cells through LncRNA HIF1A-AS2., PMID:40448168

Targeting casein kinase 2 and ubiquitin-specific protease 7 to modulate RUNX2-mediated osteogenesis in chronic kidney disease., PMID:40447997

Phytochemical Properties of (-)-Epicatechin Promotes Bone Regeneration Inducing Osteogenic Markers Expression BMP2, SPARC, and RUNX2 in Mesenchymal Stem Cells In Vitro., PMID:40444298

Insights into the potential role of BMSCs-exo delivered USP14 on SIRT1 deubiquitination in Staphylococcus aureus-induced model of osteomyelitis., PMID:40442730

A-485 alleviates postmenopausal osteoporosis by activating GLUD1 deacetylation through the SENP1-Sirt3 signal pathway., PMID:40442713

Geraniin Promotes Osteoblast Proliferation, Bone Formation, and Autophagy by Regulating the PI3K/Akt/mTOR Cascade to Improve Glucocorticoid-Induced Osteoporosis., PMID:40442527

RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth., PMID:40442075

Chondrocyte maturation bridges two cross-inhibitory subnetworks of the skeletal cell gene regulatory network., PMID:40440101

The people behind the papers - Brian Eames., PMID:40440100

Gastrodin promotes osteogenic differentiation by stimulating the Wnt/β-catenin signaling pathway., PMID:40436074

Exosomal miR-574-3p from adipose-derived mesenchymal stem modulates CRIM1/BMPs signaling to restrain chondrocytes hypertrophy and inflammatory response in knee osteoarthritis., PMID:40435818

Fibroblast growth factor 2 stimulates differentiation of mechanically-stressed human periodontal ligament fibroblasts into cementoblasts., PMID:40434329

GDF11 Alleviates Vascular Calcification in VitD3-Overloaded Mice Through Inhibition of Inflammatory NF-κB Signal., PMID:40432427

In Silico Screening and Identification of Functional Peptides from Yak Bone Collagen Hydrolysates: Antioxidant and Osteoblastic Activities., PMID:40429715

Incorporation of Zinc Oxide Nanoparticles Biosynthesized from Epimedium brevicornum Maxim. into PCL Nanofibers to Enhance Osteogenic Differentiation of Periodontal Ligament Stem Cells., PMID:40429032

Investigating the Associations Between Hmga2 Overexpression, R-Loop Reduction, and Bone Loss in Aging Mice., PMID:40428778

Regulatory Roles of E3 Ubiquitin Ligases and Deubiquitinases in Bone., PMID:40427572

Capsaicin counteracts dexamethasone-induced osteoporosis and metabolic disturbances in rats: role of AMPK/SIRT1/β-catenin/RUNX2 pathway., PMID:40425907

Metformin-Enhanced Secretome from Periodontal Ligament Stem Cells Promotes Functional Recovery in an Inflamed Periodontal Model: In Vitro Study., PMID:40422841

7-Hydroxyflavone Mitigates Osteoporosis Via Key Signaling Pathways in a Dexamethasone-induced Rat Model., PMID:40415321

Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations., PMID:40411668

Enhancing radiosensitivity of osteosarcoma by ITGB3 knockdown: a mechanism linked to enhanced osteogenic differentiation status through JNK/c-JUN/RUNX2 pathway activation., PMID:40410897

A RUNX2 GFP reporter is expressed prior to osteochondral differentiation and models Metaphyseal Dysplasia with Maxillary Hypoplasia and Brachydactyly (MDMHB)., PMID:40406460

Sodium Benzoate Inhibits Osteoblast Differentiation and Accelerates Bone Loss by Regulating the FGF2/p38/RUNX2 Pathway., PMID:40404584

Anti-osteoporotic effect of sitagliptin in an osteoporosis model of ovariectomized rats: role of RUNX2 and RANKL/OPG ratio., PMID:40397119

Compressive Force Inhibits Osteogenic Differentiation of Dental Follicle Stem Cells Through Biglycan/Bone Morphogenetic Protein2/Smad1 Signaling Pathway., PMID:40395190

Zinc valproic acid complex promotes osteoblast differentiation and exhibits anti-osteoporotic potential., PMID:40391193

3D printed PHB-dextran-whitlockite porous construct coated with sildenafil-loaded nanofibers: a hybrid scaffold for craniofacial reconstruction., PMID:40389012

Ellagic acid suppresses the human renal carcinoma cell migration and invasion by targeting the RUNX2/MMP1 expression., PMID:40386045

Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway., PMID:40383222

Yoda1-Loaded Microfibrous Scaffolds Accelerate Osteogenesis through Piezo1-F-Actin Pathway-Mediated YAP Nuclear Localization and Functionalization., PMID:40377908

SEC24D depletion induces osteogenic differentiation deficiency by inactivating the ATF6/TGF-β/Runx2 regulatory loop., PMID:40374976

Stem cell-mediated bone regeneration of marine-derived fibrinolytic compound (FGFC-1) loaded carboxymethyl chitosan hydrogels., PMID:40373628

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Mouse RUNX2 Protein, N-His [YMG67902]
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