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Anti-Human COL4A3 Antibody (SAb2252)

Catalog #:   RHF90301 Specific References (49) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, FCM
Accession: Q01955
Overview

Catalog No.

RHF90301

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Target

Goodpasture antigen, Collagen alpha-3(IV) chain, COL4A3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q01955

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAb2252

Data Image
References

Denovo glomerulonephritis associated with IgA anti-GBM alloantibodies after kidney transplantation in Alport syndrome: A case report with diagnostic implications., PMID:39237079

X-linked Alport syndrome presenting in mother and son with the same unique histopathological features., PMID:38668984

PDGF-D Is Dispensable for the Development and Progression of Murine Alport Syndrome., PMID:38309427

A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome., PMID:35140116

COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy., PMID:34326188

Neutralization of IL-6 inhibits formation of autoreactive TH17 cells but does not prevent loss of renal function in experimental autoimmune glomerulonephritis., PMID:34015360

Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease., PMID:33893224

The clinical and immunological features of the post-extracorporeal shock wave lithotripsy anti-glomerular basement membrane disease., PMID:33435789

Epitope Mapping of Human α3(IV)NC1-Induced Membranous Nephropathy in Mice., PMID:31927545

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress., PMID:31907991

Plasma exchange in anti-glomerular basement membrane disease., PMID:31703956

Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway., PMID:31146816

Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort., PMID:30935391

Inhibitory Anti-Peroxidasin Antibodies in Pulmonary-Renal Syndromes., PMID:30279272

COL4A3 Gene Variants and Diabetic Kidney Disease in MODY., PMID:30012629

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction., PMID:29731111

Routinely used immunoassays do not detect circulating anti-GBM antibodies against native NC1 hexamer and EA epitope of the α3 chain of type IV collagen., PMID:29644627

A unique evolution of the kidney phenotype in a patient with autosomal recessive Alport syndrome., PMID:29530752

Rapidly progressive glomerulonephritis due to anti-glomerular basement membrane disease accompanied by IgA nephropathy: An unusual association., PMID:29265054

Atypical antiglomerular basement membranes disease with nephrotic-range proteinuria, mesangial proliferation, and membranoproliferative glomerulonephritis pattern of injury., PMID:29265053

The critical amino acids of a nephritogenic epitope on human Goodpasture autoantigen for binding to HLA-DRB1*1501., PMID:28570922

Antibodies against linear epitopes on Goodpasture autoantigen in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:28550388

The pathogenicity of T cell epitopes on human Goodpasture antigen and its critical amino acid motif., PMID:28296059

Neuropilin1 regulates glomerular function and basement membrane composition through pericytes in the mouse kidney., PMID:27988210

Macroscopic hematuria with normal renal biopsy-following the chain to the diagnosis: Answers., PMID:26628280

Formation of vascular network structures within cardiac cell sheets from mouse embryonic stem cells., PMID:31245454

[GOODPASTURE'S SYNDROME--CASE REPORTS]., PMID:26380476

Human anti-α3(IV)NC1 antibody drug conjugates target glomeruli to resolve nephritis., PMID:26290372

Role of platelet-derived growth factor-CC in capillary rarefaction in renal fibrosis., PMID:26216283

TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis., PMID:25965582

Identification of critical residues of linear B cell epitope on Goodpasture autoantigen., PMID:25874890

Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity'., PMID:25841937

Glomerulopathy induced by immunization with a peptide derived from the goodpasture antigen α3IV-NC1., PMID:25769923

A case of subepidermal blistering disease with autoantibodies to multiple laminin subunits who developed later autoantibodies to alpha-5 chain of type IV collagen associated with membranous glomerulonephropathy., PMID:25633161

MMP mediated degradation of type IV collagen alpha 1 and alpha 3 chains reflects basement membrane remodeling in experimental and clinical fibrosis--validation of two novel biomarker assays., PMID:24376856

Neonatal Fc receptor promotes immune complex-mediated glomerular disease., PMID:24357670

In vivo imaging of disease-modified glomerular extracellular matrix in renal disease., PMID:23903419

Quaternary epitopes of α345(IV) collagen initiate Alport post-transplant anti-GBM nephritis., PMID:23620401

A human monoclonal antibody against the collagen type IV α3NC1 domain is a non-invasive optical biomarker for glomerular diseases., PMID:23515049

Prognostic value of glomerular collagen IV immunofluorescence studies in male patients with X-linked Alport syndrome., PMID:23371956

Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers., PMID:23303673

Precise mapping of the Goodpasture epitope(s) using phage display, site-directed mutagenesis, and surface plasmon resonance., PMID:23254898

Association of epitope spreading of antiglomerular basement membrane antibodies and kidney injury., PMID:23085731

Antibodies against linear epitopes on the Goodpasture autoantigen and kidney injury., PMID:22461538

Genetic susceptibility to experimental autoimmune glomerulonephritis in the Wistar Kyoto rat., PMID:22445570

Characterization of the renal CD4+ T-cell response in experimental autoimmune glomerulonephritis., PMID:22437418

Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome., PMID:22371398

Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells alone., PMID:22244885

Analysis of the role of ZEB1 in the pathogenesis of posterior polymorphous corneal dystrophy., PMID:22199242

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human COL4A3 Antibody (SAb2252) [RHF90301]
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