Catalog No.
RXX08401
Species reactivity
Staphylococcus aureus
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Cas9, CRISPR-associated endonuclease Cas9/Csn1, CRISPR-Cas9/Csn1, csn1, SpyCas9, CRISPR Cas9 SA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
J7RUA5
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2T13
Pathophysiological mechanisms of hair follicle regeneration and potential therapeutic strategies., PMID:40518544
Cas9- and Cas12a-mediated excision and replacement of the celiac disease-related α-gliadin immunogenic complex in hexaploid wheat., PMID:40517395
Protocol for genetic dissection of class switch recombination using genome-editing tools., PMID:40482035
ZBED6 Knockout Prevents Ageing- and Dexamethasone-Induced Muscle Atrophy via Dkk3 in Pig and Mice., PMID:40464206
Generation of iPSC lines with tagged α-synuclein for visualization of endogenous protein in human cellular models of neurodegenerative disorders., PMID:40456614
Bacteriophages as Targeted Therapeutic Vehicles: Challenges and Opportunities., PMID:40428088
Current and emerging treatment options for transthyretin amyloid cardiomyopathy., PMID:40425273
Immunogenicity evaluation of a recombinant pseudorabies virus co-expressing PCV2 and PCV3 capsid proteins in mice and piglets., PMID:40424702
Genomic and Phenotypic Characterization of CHO 4BGD Cells with Quad Knockout and Overexpression of Two Housekeeping Genes That Allow for Metabolic Selection and Extended Fed-Batch Culturing., PMID:40422195
An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors., PMID:40410803
Harnessing mechanobiology to enhance cell therapy., PMID:40395223
Immune checkpoint inhibitor (ICI) therapy in central nervous system cancers: State-of-the-art and future outlook., PMID:40394797
Generation of Hoxa11-3XFLAG and Hoxd11-3XFLAG alleles to investigate Hox11 genome-wide binding., PMID:40389054
A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain., PMID:40354542
Construction of Two Recombinant Pseudorabies Viruses with Deletion of Virulence Genes and Evaluation of Their Immune Protection in Mice and Piglets., PMID:40333253
Identification of TSSK1 and TSSK2 as Novel Targets for Male Contraception., PMID:40305308
Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer., PMID:40299475
Permanent Efferocytosis Prevention by Terminating MerTK Recycle on Tumor-Associated Macrophages for Cancer Immunotherapy., PMID:40294287
Two CENH3 paralogs in the green alga Chlamydomonas reinhardtii have a redundantly essential function and associate with ZeppL-LINE1 elements., PMID:40289909
Generation of hiPSC lines with fusion tagged thyroid hormone receptor α isoforms to study isoform-specific actions of TRα1 and TRα2., PMID:40286604
Humanized mouse model reveals the immunogenicity of Hepatitis B Virus vaccine candidates produced in CRISPR/Cas9-edited Nicotiana benthamiana., PMID:40270959
CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis., PMID:40268165
Exploration of a GMMA-Based Bivalent Vaccine Against Klebsiella pneumoniae., PMID:40266066
Adeno-associated virus-clustered regularly interspaced short palindromic repeats/cas9‑mediated ovarian cancer treatment targeting PD-L1., PMID:40264105
Clinical perspective: Advancing hemophilia treatment through gene therapy approaches., PMID:40263938
Characterization of a novel Leishmania antigen containing a repetitive domain and its potential use as a prophylactic and therapeutic vaccine., PMID:40261025
pIgR-like4.2 enhances the antiviral immune response of zebrafish against spring viremia of carp virus., PMID:40250506
Etiological Treatment of Cardiac Amyloidosis: Standard of Care and Future Directions., PMID:40232627
Systematic identification of genomic hotspots for high-yield protein production in CHO cells., PMID:40228657
Innovations in Bacteriophage Genome Engineering for Combating Multidrug-Resistant Bacterial Infections., PMID:40216545
A novel micronemal protein MP38 is involved in the invasion of merozoites into erythrocytes., PMID:40202329
Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation., PMID:40190036
Construction and characterization of a gE/gI/TK-gene-deleted recombinant pseudorabies virus variant expressing the GP5 of the highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) and NADC30-like PRRSV., PMID:40180235
Corrigendum: Transient proteolysis reduction of Nicotiana benthamiana-produced CAP256 broadly neutralizing antibodies using CRISPR/Cas9., PMID:40177014
CRISPR screens with trastuzumab emtansine in HER2-positive breast cancer cell lines reveal new insights into drug resistance., PMID:40165206
Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies., PMID:40164595
Dual blockade of GSTK1 and CD47 improves macrophage-mediated phagocytosis on cancer cells., PMID:40147800
Clinical development of therapeutic mRNA applications., PMID:40143545
Enhancing human NK cell antitumor function by knocking out SMAD4 to counteract TGFβ and activin A suppression., PMID:40119192
IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer., PMID:40091029
A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity., PMID:40060628
CD38 in the pathobiology of cutaneous T-cell lymphoma and the potential for combination therapeutic intervention., PMID:40057636
Subunit vaccine of PCV3 capsid protein produced by sf9 cells with double knockout of Caspase-1 and Dronc induces strong immune response in mice., PMID:40056704
Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy., PMID:40056044
Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing., PMID:40055516
Cleavage of the selective autophagy receptor NBR1 by the PDCoV main protease NSP5 impairs autophagic degradation of the viral envelope protein., PMID:40047225
CRISPR/Cas9 Methods for Identification and Validation of Genes Regulating BCR-Mediated Antigen Uptake., PMID:40029521
STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia., PMID:40009483
Engineering Base Changes and Epitope-Tagged Alleles in Mice Using Cas9 RNA-Guided Nuclease., PMID:39999224
HIV cure-related research: where we stand and where we go., PMID:39998392
For research use only. Not for human or drug use.
