Catalog No.
RMN90001
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Ly-6A.2/Ly-6E.1, Ly6a, Ly6al, Lymphocyte antigen 6A-2/6E-1, Lymphocyte antigen Ly 6A.2/Ly 6E.1, SCA-1, Stem cell antigen 1, T cell activating protein, TAP, Ly6a
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05533
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2T10
Crosslinking of Ly6a metabolically reprograms CD8 T cells for cancer immunotherapy., PMID:39333093
The bone marrow endothelial progenitor cell response to septic infection., PMID:38665923
Development of CNS tropic AAV1-like variants with reduced liver-targeting following systemic administration in mice., PMID:38297833
Ly-6A-Induced Growth Inhibition and Cell Death in a Transformed CD4+ T Cell Line: Role of Tumor Necrosis Factor-α., PMID:36725744
Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota., PMID:36316480
Novel Sca-1+ macrophages modulate the pathogenic progress of endotoxemia., PMID:32919702
Circulation of gut-preactivated naïve CD8+ T cells enhances antitumor immunity in B cell-defective mice., PMID:32907933
Novel CD11b+Gr-1+Sca-1+ myeloid cells drive mortality in bacterial infection., PMID:32010784
Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids., PMID:31725765
Thy-1 (CD90) Signaling Preferentially Promotes RORγt Expression and a Th17 Response., PMID:30533413
Evaluation of the bioactivity about anti-sca-1/basic fibroblast growth factor-urinary bladder matrix scaffold for pelvic reconstruction., PMID:30426863
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow., PMID:29934585
Bone marrow PDGFRα+Sca-1+-enriched mesenchymal stem cells support survival of and antibody production by plasma cells in vitro through IL-6., PMID:29529192
Engaging Ly-6A/Sca-1 triggers lipid raft-dependent and -independent responses in CD4+ T-cell lines., PMID:28660664
A depleting antibody toward sca-1 mitigates a surge of CD34(+)/c-kit(+) progenitors and reduces vascular restenosis in a murine vascular injury model., PMID:27666446
Investigating B Cell Development, Natural and Primary Antibody Responses in Ly-6A/Sca-1 Deficient Mice., PMID:27322740
Sca-1(+) mesenchymal stromal cells inhibit splenic marginal zone B lymphocytes commitment through Caspase-3., PMID:26861667
The Murine Bladder Supports a Population of Stromal Sca-1+/CD34+/lin- Mesenchymal Stem Cells., PMID:26540309
CD201 and CD27 identify hematopoietic stem and progenitor cells across multiple murine strains independently of Kit and Sca-1., PMID:25892186
Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism., PMID:25563724
Isolation and characterization of a Sca-1+/CD31- progenitor cell lineage derived from mouse heart tissue., PMID:25106452
Expression of dual nucleotides/cysteinyl-leukotrienes receptor GPR17 in early trafficking of cardiac stromal cells after myocardial infarction., PMID:24909956
Molecular profiling of single Sca-1+/CD34+,- cells--the putative murine lung stem cells., PMID:24391845
Stem cell antigen 1-positive mesenchymal cells are the origin of follicular cells during thyroid regeneration., PMID:24278321
Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium., PMID:23621987
Toll-like receptor 4/stem cell antigen 1 signaling promotes hematopoietic precursor cell commitment to granulocyte development during the granulopoietic response to Escherichia coli bacteremia., PMID:23545304
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation., PMID:23299888
Distribution and homing pattern of c-kit+ Sca-1+ CXCR4+ resident cardiac stem cells in neonatal, postnatal, and adult mouse heart., PMID:23273785
Donor hematopoietic stem cells confer long-term marrow reconstitution by self-renewal divisions exceeding to that of host cells., PMID:23227199
Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α., PMID:23154782
Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions., PMID:23071158
Exogenous, TAP-independent lysosomal presentation of a respiratory syncytial virus CTL epitope., PMID:22929180
Host-derived pericytes and Sca-1+ cells predominate in the MART-1- stroma fraction of experimentally induced melanoma., PMID:22147606
Detection of hematopoietic stem cells by flow cytometry., PMID:21722798
Stem-cell-capturing collagen scaffold promotes cardiac tissue regeneration., PMID:21227504
Isolation and propagation of mesenchymal stem cells from the lacrimal gland., PMID:21178145
Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat., PMID:21173238
Protective effects of statin on cardiac fibrosis and apoptosis in adrenomedullin-knockout mice treated with angiotensin II and high salt loading., PMID:21160482
Embryonic stem cell-derived cardiomyocytes harbor a subpopulation of niche-forming Sca-1+ progenitor cells., PMID:21127947
Sca-1 influences the innate immune response during skeletal muscle regeneration., PMID:21123737
Quantitative assessment of initial retention of bone marrow mononuclear cells injected into the coronary arteries., PMID:20971657
Sca-1 expression pattern in the mouse limbal epithelium and its association with cell cycle., PMID:22049616
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells., PMID:20023630
Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model., PMID:19887604
Overexpression of sonic Hedgehog in the lung mimics the effect of lung injury and compensatory lung growth on pulmonary Sca-1 and CD34 positive cells., PMID:19861952
Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy., PMID:19380767
Multiplex immunoassay using fluorescent-surface enhanced Raman spectroscopic dots for the detection of bronchioalveolar stem cells in murine lung., PMID:19117480
Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics., PMID:19056905
Intranasal HGF administration ameliorates the physiologic and morphologic changes in lung emphysema., PMID:18560414
Stem cell antigen-1 localizes to lipid microdomains and associates with insulin degrading enzyme in skeletal myoblasts., PMID:18506847
For research use only. Not for human or drug use.
