Catalog No.
RHN88201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
Cerebral protein 6, BAP1, Ubiquitin carboxyl-terminal hydrolase BAP1, BRCA1-associated protein 1, KIAA0272
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92560
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2S89
Molecular Mechanisms of Tumor Progression and Novel Therapeutic and Diagnostic Strategies in Mesothelioma., PMID:40362535
BAP1-mediated ubiquitination inhibition and CAS6/AXL signaling activation in bladder cancer progression., PMID:40330545
A model workflow for microfluidic enrichment and genetic analysis of circulating melanoma cells., PMID:40316673
Spitz Spindle Cell/Reed Nevus With SQSTM1 :: NTRK2 Fusion and Atypical Features in an Older Male Patient: A Case Report and Review of Literature., PMID:39980385
A neoantigen vaccine generates antitumour immunity in renal cell carcinoma., PMID:39910301
PRAME Immunostaining in BAP-1-Inactivated Melanocytic Tumors: Unraveling Diagnostic Complexity and Exploring Germline Mutation Associations., PMID:39761650
Biomarker analyses from the phase III randomized CLEAR trial: lenvatinib plus pembrolizumab versus sunitinib in advanced renal cell carcinoma., PMID:39672382
Primary extraskeletal osteosarcomas of the pleura: A clinicopathological, immunohistochemical, and molecular analysis of 4 cases., PMID:39117026
Utility of next-generation sequencing in the diagnosis of metastatic melanoma: A case report., PMID:38757469
B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1., PMID:38529289
Characterizations of uveal melanoma patients with three additional primary malignancies., PMID:38229427
Complete clinical remission of malignant peritoneal mesothelioma with systemic pemetrexed and bevacizumab in a patient with a BAP1 mutation., PMID:38142057
Niraparib plus Dostarlimab in Pleural Mesothelioma or Non-Small Cell Lung Cancer Harboring HRR Mutations: Interim Results of the UNITO-001 Phase II Prospective Trial., PMID:38109438
An Overview of Renal Cell Carcinoma Hallmarks, Drug Resistance, and Adjuvant Therapies., PMID:37927802
Immunohistochemical Characterization of a Large Cohort of Triple Negative Breast Cancer., PMID:37306115
Apoptotic cell death in disease-Current understanding of the NCCD 2023., PMID:37100955
[Pathoanatomical algorithm for differential diagnosis of Paget's disease of the breast]., PMID:37053351
BAP1-related signature predicts benefits from immunotherapy over VEGFR/mTOR inhibitors in ccRCC: a retrospective analysis of JAVELIN Renal 101 and checkmate-009/010/025 trials., PMID:37046008
Data supporting the roles of BAP1, STING, and IFN-β in ISGF3 activation in ccRCC., PMID:36426057
Comprehensive Analysis of HMCN1 Somatic Mutation in Clear Cell Renal Cell Carcinoma., PMID:35886066
CD117, BAP1, MTAP, and TdT Is a Useful Immunohistochemical Panel to Distinguish Thymoma from Thymic Carcinoma., PMID:35565429
Evaluation of HSP-27, BAP1, BRAF V600E, CCR7, and PD-L1 expression in uveal melanoma on enucleated eyes and metastatic liver tumors., PMID:35341390
LZTS2: A novel and independent prognostic biomarker for clear cell renal cell carcinoma., PMID:35287088
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial., PMID:34750557
Molecular predictors of response to pembrolizumab in thymic carcinoma., PMID:34622229
LAG3 and Its Ligands Show Increased Expression in High-Risk Uveal Melanoma., PMID:34503258
The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal melanoma., PMID:34453044
The WHO 2018 Classification of Cutaneous Melanocytic Neoplasms: Suggestions From Routine Practice., PMID:34277420
Diagnostic Utility of BAP1, EZH2 and Survivin in Differentiating Pleural Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia: Immunohistochemical Study., PMID:34257556
Genomic Landscape of Chinese Clear Cell Renal Cell Carcinoma Patients With Venous Tumor Thrombus Identifies Chromosome 9 and 14 Deletions and Related Immunosuppressive Microenvironment., PMID:34249685
When the Diagnosis of Mesothelioma Challenges Textbooks and Guidelines., PMID:34070888
How to Make Immunotherapy an Effective Therapeutic Choice for Uveal Melanoma., PMID:33922591
Molecular and immunohistochemical evaluation of BAP-1 antibody in bladder cancer and comparison with luminal-basal subtyping., PMID:33341088
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma., PMID:33318203
Mesothelioma Biomarkers: Discovery in Search of Validation., PMID:33012429
Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer., PMID:32690542
Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma., PMID:32472114
BAP-1 Expression Status by Immunohistochemistry in Cellular Blue Nevus and Blue Nevus-like Melanoma., PMID:32310893
Distinct clinical and prognostic implication of IDH1/2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma., PMID:32293336
This special volume of mesothelioma is dedicated to my friend Adi Gazdar., PMID:32206566
The value of BRCA-1-associated protein 1 expression and cyclin-dependent kinase inhibitor 2A deletion to distinguish peritoneal malignant mesothelioma from peritoneal location of carcinoma in effusion cytology specimens., PMID:31713897
Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials., PMID:31285588
About the diagnostic value of BAP-1 antibody in malignant pleural mesothelioma: a meta-analysis., PMID:30810450
Expression of an scFv antibody fragment in Nicotiana benthamiana and in vitro assessment of its neutralizing potential against the snake venom metalloproteinase BaP1 from Bothrops asper., PMID:30802471
The role of BRCA1-associated protein 1 in the diagnosis of malignant mesothelioma in effusion and fine-needle aspiration cytology., PMID:30520251
BAP1 regulates different mechanisms of cell death., PMID:30455474
Malignant peritoneal mesothelioma: a review., PMID:30450291
Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1., PMID:30349006
Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma., PMID:30060843
Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes., PMID:29678836
For research use only. Not for human or drug use.
