Catalog No.
RHN74501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Friend of EBNA2 protein, Wings apart-like protein homolog, FOE, KIAA0261, WAPAL, WAPL, WAPL cohesin release factor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q7Z5K2
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2R14
Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932
Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination., PMID:37339228
Contribution of the IGCR1 regulatory element and the 3 'Igh CBEs to Regulation of Igh V(D)J Recombination., PMID:37163018
Igh and Igk loci use different folding principles for V gene recombination due to distinct chromosomal architectures of pro-B and pre-B cells., PMID:37085514
Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells., PMID:34465007
Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination., PMID:33679727
Loop extrusion mediates physiological Igh locus contraction for RAG scanning., PMID:33442057
How DNA loop extrusion mediated by cohesin enables V(D)J recombination., PMID:33422934
Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion., PMID:32612238
The inhibitory effect of a new scFv/tP protein as siRNA delivery system to target hWAPL in cervical carcinoma., PMID:24567178
Wapl localization on the synaptonemal complex, a meiosis-specific proteinaceous structure that binds homologous chromosomes, in the female mouse., PMID:18199270
The complete removal of cohesin from chromosome arms depends on separase., PMID:18003702
Immunization of mice with plasmids coexpressing HPV16 E5 and the novel oncogene hWAPL., PMID:17645509
[Prokaryotic expression and immunogenicity of hWAPL, a norel oncogene related to cervical cancer]., PMID:17553356
For research use only. Not for human or drug use.
