Catalog No.
RHN67702
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
CDCA1, NUF2, Kinetochore protein Nuf2, hNuf2, hNuf2R, hsNuf2, NUF2R, Cell division cycle-associated protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9BZD4
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2Q20
Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer., PMID:27499128
Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers., PMID:24247253
The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores., PMID:22454517
Relative contributions of chromatin and kinetochores to mitotic spindle assembly., PMID:19805628
Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1., PMID:19776357
Chromosome congression in the absence of kinetochore fibres., PMID:19525938
ICIS and Aurora B coregulate the microtubule depolymerase Kif2a., PMID:19327998
Molecular organization of the Ndc80 complex, an essential kinetochore component., PMID:15809444
Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites., PMID:15548592
The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK., PMID:15302853
Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1., PMID:15235793
The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment., PMID:14738735
Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores., PMID:14654001
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity., PMID:12514103
Nuf2, a spindle pole body-associated protein required for nuclear division in yeast., PMID:8188751