Catalog No.
RRN11801
Species reactivity
Mouse, Rat, Hamster
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20, WB: 1:500-1:1000
Target
Fzo homolog, Transmembrane GTPase MFN1, MFN1, Mitofusin-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8R4Z9
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N52
Mitochondrial-Mediated Platelet Activation in Polymyalgia Rheumatica., PMID:40071558
Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells., PMID:39906960
MEHP induced mitochondrial damage by promoting ROS production in CIK cells, leading to apoptosis, autophagy, cell cycle arrest., PMID:39586385
Interleukin-6 Facilitates Acute Myeloid Leukemia Chemoresistance via Mitofusin 1-Mediated Mitochondrial Fusion., PMID:37698549
Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells., PMID:37292700
Engineering nanoparticles boost TNBC therapy by CD24 blockade and mitochondrial dynamics regulation., PMID:36736908
Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus., PMID:35128841
Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages., PMID:33356389
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., PMID:32249716
Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1., PMID:31181072
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Expression of mitochondrial dynamics markers during melanoma progression: Comparative study of head and neck cutaneous and mucosal melanomas., PMID:30916813
Effect of Qiangji Jianli decoction on mitochondrial respiratory chain activity and expression of mitochondrial fusion and fission proteins in myasthenia gravis rats., PMID:29872094
Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells., PMID:31966653
Cell-free mitochondrial fusion assay detected by specific protease reaction revealed Ca2+ as regulator of mitofusin-dependent mitochondrial fusion., PMID:28460043
p38 MAP kinase-dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER-mitochondria association and mitochondria motility., PMID:26337390
Mitochondrial fusion provides an 'initial metabolic complementation' controlled by mtDNA., PMID:25708700
Cell type-specific subcellular localization of phospho-TBK1 in response to cytoplasmic viral DNA., PMID:24349538
Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins., PMID:22961849
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse., PMID:22769563
Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner., PMID:22484496
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage., PMID:21459773
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease., PMID:20660112
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease., PMID:19605646
Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons., PMID:19445933
Mitochondrial biogenesis in the axons of vertebrate peripheral neurons., PMID:18666204
Control of mitochondrial morphology by a human mitofusin., PMID:11181170
For research use only. Not for human or drug use.
