Catalog No.
RHK90801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IHC: 1:100-1:200
Target
Anoctamin-1, Tumor-amplified and overexpressed sequence 2, Transmembrane protein 16A, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, TMEM16A, ANO1, TAOS2, ORAOV2, DOG1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q5XXA6
Applications
FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N26
Functional roles of interstitial cells of Cajal in the GI tract of rats., PMID:40235202
A Cftr-independent, Ano1-rich seawater-adaptive ionocyte in sea lamprey gills., PMID:40007443
Co-targeting TMEM16A with a novel monoclonal antibody and EGFR with Cetuximab inhibits the growth and metastasis of esophageal squamous cell carcinoma., PMID:39563381
Gastrointestinal Stromal Tumors: Variants and Some Pitfalls That They Create., PMID:39466697
Involvement of TRPV4 in temperature-dependent perspiration in mice., PMID:38963781
Establishing an ANO1-Based Cell Model for High-Throughput Screening Targeting TRPV4 Regulators., PMID:38474548
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization., PMID:37749499
ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle., PMID:37702787
Establishment of a Cell Model for Dynamic Monitoring of Intracellular Calcium Concentration and High-Throughput Screening of P2Y2 Regulators., PMID:35566353
Anoctamin 1 and c-Kit immunohistochemical study of interstitial cells of Cajal in the muscularis externa of human gastrointestinal tract., PMID:35037698
DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness., PMID:34414034
Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells., PMID:34243598
TMEM16A-encoded anoctamin 1 inhibition contributes to chrysin-induced coronary relaxation., PMID:33152928
TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection., PMID:33109690
Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling., PMID:32517157
Immunohistochemical analysis of 36 cases of chondroblastomas: A single institutional experience., PMID:31862519
ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion., PMID:31564164
Telocytes express ANO-1-encoded chloride channels in canine ventricular myocardium., PMID:31293701
A Novel Dual Immunostain to Characterize Sloughed Cells in Testicular Biopsies for Infertility., PMID:31094926
TMEM16A as a Potential Biomarker in the Diagnosis and Prognosis of Lung Cancer., PMID:30821158
Intraluminal pressure triggers myogenic response via activation of calcium spark and calcium-activated chloride channel in rat renal afferent arteriole., PMID:30089032
[Gastrointestinal leiomyoma with interstitial cells of Cajal: mimicker of gastrointestinal stromal tumor]., PMID:29886588
TMEM16A inhibition impedes capacitation and acquisition of hyperactivated motility in guinea pig sperm., PMID:29600587
Ultrastructural and Immunohistochemical Features of Telocytes in Placental Villi in Preeclampsia., PMID:29472628
Epithelial disruptions, but not immune cell invasion, induced secretory dysfunction following innate immune activation in a novel model of acute salivary gland injury., PMID:29160910
Expression of dog1 in low-grade fibromyxoid sarcoma: A study of 19 cases and review of the literature., PMID:28965630
[Gastrointestinal stromal tumor and renal transplant]., PMID:28825581
Circulating Biomarkers for Predicting Infliximab Response in Rheumatoid Arthritis: A Systematic Bioinformatics Analysis., PMID:28413214
TMEM16A/ANO1 suppression improves response to antibody-mediated targeted therapy of EGFR and HER2/ERBB2., PMID:28177558
Interstitial cell modulation of pyeloureteric peristalsis in the mouse renal pelvis examined using FIBSEM tomography and calcium indicators., PMID:28054154
The Diagnostic and Prognostic Utility of DOG1 Expression on Gastrointestinal Stromal Tumors., PMID:28044310
The stem cell growth factor receptor KIT is not expressed on interstitial cells in bladder., PMID:27997763
The presence and role of interstitial cells of Cajal in the proximal intestine of shorthorn sculpin (Myoxocephalus scorpius)., PMID:27875260
Transcriptional repression of HER2 by ANO1 Cl- channel inhibition in human breast cancer cells with resistance to trastuzumab., PMID:27838298
Effects of Exogenous Interleukin-9 on the Growth, Proliferation and Activity of Interstitial Cells of Cajal Cultured in vitro., PMID:27832662
Expression of DOG1 (Using SP31) in Poorly Differentiated Carcinoma of the Head and Neck., PMID:27272836
Altered tryptophan hydroxylase 2 expression in enteric serotonergic nerves in Hirschsprung's-associated enterocolitis., PMID:27217698
Telocytes (interstitial Cajal-like cells) in human Fallopian tubes., PMID:27215957
PDGFRA and KIT Mutation Status and Its Association With Clinicopathological Properties, Including DOG1., PMID:27178821
Is DOG1 Immunoreactivity Specific to Gastrointestinal Stromal Tumor?, PMID:26678977
Anoctamin 1 (Ano1) is required for glucose-induced membrane potential oscillations and insulin secretion by murine β-cells., PMID:26582426
Use of anoctamin 1 (ANO1) to evaluate interstitial cells of Cajal in Hirschsprung's disease., PMID:26510736
Correlation of angiogenesis with other immunohistochemical markers in cutaneous basal and squamous cell carcinomas., PMID:26429157
DOG1 Expression in Low-Grade Fibromyxoid Sarcoma: A Study of 11 Cases, With Molecular Characterization., PMID:26135531
Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats., PMID:26130088
Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin., PMID:26121472
Characterization of Cardiac Anoctamin1 Ca²⁺-Activated Chloride Channels and Functional Role in Ischemia-Induced Arrhythmias., PMID:24962810
Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice., PMID:24758567
The multiple expression of Ca²⁺-activated Cl⁻ channels via homo- and hetero-dimer formation of TMEM16A splicing variants in murine portal vein., PMID:24321548
Anoctamin 1 positive esophageal interstitial Cajal cells in late stage human embryos., PMID:24243583
For research use only. Not for human or drug use.
