Catalog No.
RHK81902
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
EVN, Artemin, Enovin, ARTN, Neublastin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q5T4W7
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N13
The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8., PMID:39552306
Proteomic analysis of plasma in healthy adults receiving recombinant vaccinia virus provides novel insights into HIV-1 neutralizing antibodies., PMID:38888113
Artemin Is Upregulated by TrkB Agonist and Protects the Immature Retina Against Hypoxic-Ischemic Injury by Suppressing Neuroinflammation and Astrogliosis., PMID:33912011
Primary hypothyroidism and autoimmune thyroiditis alter the transcriptional activity of genes regulating neurogenesis in the blood of patients., PMID:33600668
Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRα3-ERK pathway in pancreatic ductal adenocarcinoma., PMID:33236361
Aryl Hydrocarbon Receptor Directly Regulates Artemin Gene Expression., PMID:31358547
Sequestration of artemin reduces inflammation-induced activation and sensitization of bone marrow nociceptors in a rodent model of carrageenan-induced inflammatory bone pain., PMID:30218545
Artemin promotes oncogenicity, metastasis and drug resistance in cancer cells., PMID:28937965
Inflammatory and neuropathic cold allodynia are selectively mediated by the neurotrophic factor receptor GFRα3., PMID:27051069
Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma., PMID:26675549
Involvement of peripheral artemin signaling in tongue pain: possible mechanism in burning mouth syndrome., PMID:26270588
Artemin Immunotherapy Is Effective in Preventing and Reversing Cystitis-Induced Bladder Hyperalgesia via TRPA1 Regulation., PMID:25892657
A soluble form of GAS1 inhibits tumor growth and angiogenesis in a triple negative breast cancer model., PMID:24992044
Artemin, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2-regulated and mediates acquired trastuzumab resistance by promoting cancer stem cell-like behavior in mammary carcinoma cells., PMID:24737320
Artemin-GFRα3 interactions partially contribute to acute inflammatory hypersensitivity., PMID:23603259
ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signalling., PMID:23185544
Antidepressant-like effect of artemin in mice: a mechanism for acetyl-L-carnitine activity on depression., PMID:21590285
Artemin Reduces Sensitivity to Doxorubicin and Paclitaxel in Endometrial Carcinoma Cells through Specific Regulation of CD24., PMID:20689763
Artemin-stimulated progression of human non-small cell lung carcinoma is mediated by BCL2., PMID:20530713
Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma., PMID:20305694
Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells., PMID:20118197
Artemin is oncogenic for human mammary carcinoma cells., PMID:19363524
Rac1 is a critical mediator of endothelium-derived neurotrophic activity., PMID:19278959
Specificity in the crosstalk of TGFbeta/GDNF family members is determined by distinct GFR alpha receptors., PMID:17953664
Vascular-derived artemin: a determinant of vascular sympathetic innervation?, PMID:17337595
Right on cue., PMID:17051228
Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret., PMID:17013378
Glial cell line-derived neurotrophic factor (GDNF) receptor alpha-1 (GFR alpha 1) is highly selective for GDNF versus artemin., PMID:15709767
For research use only. Not for human or drug use.
