Catalog No.
RHK75403
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Deubiquitinating enzyme 22, USP22, Ubiquitin thioesterase 22, Ubiquitin carboxyl-terminal hydrolase 22, KIAA1063, USP3L, Ubiquitin-specific-processing protease 22
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UPT9
Applications
IF, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2N01
Demethylzeylasteral induces PD-L1 ubiquitin-proteasome degradation and promotes antitumor immunity via targeting USP22., PMID:39525573
A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function., PMID:37747800
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice., PMID:37127227
[Plasma exosomal miR-335-5p serves as a diagnostic indicator and inhibits immune escape in triple-negative breast cancer]., PMID:35583065
Targeted eradication of gastric cancer stem cells by CD44 targeting USP22 small interfering RNA-loaded nanoliposomes., PMID:30543303
Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22., PMID:30197002
Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells., PMID:30088609
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining., PMID:29520062
Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation., PMID:25846153
Ubiquitin-specific peptidase 22 overexpression may promote cancer progression and poor prognosis in human gastric carcinoma., PMID:25445209
Regulation of cancer stem cell properties by CD9 in human B-acute lymphoblastic leukemia., PMID:21549094