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Anti-TFR2 Antibody (R2K92)

Catalog #:   RHJ82601 Specific References (30) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, WB
Accession: Q9UP52
Overview

Catalog No.

RHJ82601

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

TFR2, TfR2, Transferrin receptor protein 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UP52

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2K92

Data Image
  • Western blot
    Western blot analysis of Transferrin Receptor 2 expression in HepG2 cell lysate.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
References

Idecabtagene vicleucel or ciltacabtagene autoleucel for relapsed or refractory multiple myeloma: An international multicenter study., PMID:39822585

Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy., PMID:39632797

MOSAIC: An Artificial Intelligence-Based Framework for Multimodal Analysis, Classification, and Personalized Prognostic Assessment in Rare Cancers., PMID:38875514

Bone marrow Tfr2 deletion improves the therapeutic efficacy of the activin-receptor ligand trap RAP-536 in β-thalassemic mice., PMID:38629683

Synthetic Data Generation by Artificial Intelligence to Accelerate Research and Precision Medicine in Hematology., PMID:37390377

Decitabine Versus Hydroxyurea for Advanced Proliferative Chronic Myelomonocytic Leukemia: Results of a Randomized Phase III Trial Within the EMSCO Network., PMID:36455187

Comparison Between 5-Azacytidine Treatment and Allogeneic Stem-Cell Transplantation in Elderly Patients With Advanced MDS According to Donor Availability (VidazaAllo Study)., PMID:34283629

Phase III, Randomized, Placebo-Controlled Trial of CC-486 (Oral Azacitidine) in Patients With Lower-Risk Myelodysplastic Syndromes., PMID:33764805

Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes., PMID:33539200

Transferrin receptor 1 in cancer: a new sight for cancer therapy., PMID:30034931

Hepatocytes internalize trophic receptors at large endocytic "Hot Spots"., PMID:21793030

Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2., PMID:18561026

Transferrin receptor engagement by polymeric IgA1 induces receptor expression and mesangial cell proliferation: role in IgA nephropathy., PMID:17495453

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses., PMID:17287727

TfR2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway., PMID:17046995

Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium., PMID:17003411

Localization of the iron-regulatory proteins hemojuvelin and transferrin receptor 2 to the basolateral membrane domain of hepatocytes., PMID:16932966

The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer., PMID:16904380

Transferrin receptor-1 and 2 expression in chronic lymphocytic leukemia., PMID:16054692

Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy., PMID:15987753

Transferrin receptor 2 protein is not expressed in normal erythroid cells., PMID:15084147

Glycosylation and size of IgA1 are essential for interaction with mesangial transferrin receptor in IgA nephropathy., PMID:14978164

Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes., PMID:14563638

Molecular evidence for transferrin receptor 2 expression in all FAB subtypes of acute myeloid leukemia., PMID:12921947

Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells., PMID:12704209

Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2., PMID:12656741

Hemochromatosis due to mutations in transferrin receptor 2., PMID:12547237

Heterotypic interactions between transferrin receptor and transferrin receptor 2., PMID:12406888

Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and a polyclonal antiserum., PMID:12393650

Interaction of human Ku70 with TRF2., PMID:10984620

Datasheet

Document Download

Anti-TFR2 Antibody (R2K92).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-TFR2 Antibody (R2K92) [RHJ82601]
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