Catalog No.
RHJ75101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
hPARP-2, PARP-2, ADPRT-2, NAD(+) ADP-ribosyltransferase 2, ADPRTL2, PARP2, ARTD2, Poly[ADP-ribose] synthase 2, Protein poly-ADP-ribosyltransferase PARP2, DNA ADP-ribosyltransferase PARP2, ADPRT2, ADP-ribosyltransferase diphtheria toxin-like 2, Poly [ADP-ribose] polymerase 2, pADPRT-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UGN5
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2K73
PARP Inhibitors for Breast Cancer Treatment: A Review., PMID:38512229
A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts., PMID:38391916
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype., PMID:36223740
Recent Insights into PARP and Immuno-Checkpoint Inhibitors in Epithelial Ovarian Cancer., PMID:35886427
Analysis of the transcriptomic features of microsatellite instability subtype colon cancer., PMID:31221124
Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function., PMID:30996287
Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription., PMID:29712969
Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation., PMID:29361132
PARP inhibitors as potential therapeutic agents for various cancers: focus on niraparib and its first global approval for maintenance therapy of gynecologic cancers., PMID:29214031
Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice., PMID:28105679
Parp3 negatively regulates immunoglobulin class switch recombination., PMID:26000965
Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3., PMID:25017100
Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression., PMID:24895135
The expression pattern of PARP-1 and PARP-2 in the developing and adult mouse testis., PMID:24785709
Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis., PMID:23607899
Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance., PMID:22639866
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression., PMID:21270334
Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers., PMID:20823146
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination., PMID:19629035
Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination., PMID:19364882
Assessment of PARP-3 distribution in tissues of cynomolgous monkeys., PMID:19332431
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery., PMID:16924674
A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats., PMID:15466246
Presence of functionally active protease-activated receptors 1 and 2 in myenteric glia., PMID:12390517
Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis., PMID:11523787
For research use only. Not for human or drug use.
