Catalog No.
RHJ74802
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
SPAK, STK39, Ste-20-related kinase, STE20/SPS1-related proline-alanine-rich protein kinase, Serine/threonine-protein kinase 39, DCHT
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UEW8
Applications
FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2K71
STK39 inhibits antiviral immune response by inhibiting DCAF1-mediated PP2A degradation., PMID:40370558
WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses., PMID:39984435
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice., PMID:36662229
STK39 is a novel kinase contributing to the progression of hepatocellular carcinoma by the PLK1/ERK signaling pathway., PMID:33500714
C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity., PMID:29921588
DNPEP is not the only peptidase that produces SPAK fragments in kidney., PMID:29122955
SPAK plays a pathogenic role in IgA nephropathy through the activation of NF-κB/MAPKs signaling pathway., PMID:27519267
Endothelin-1 genetic polymorphism as predictive marker for bevacizumab in metastatic breast cancer., PMID:27139155
SPAK-mediated NCC regulation in response to low-K+ diet., PMID:25651563
Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer., PMID:24886063
Comparable autoantibody serum levels against amyloid- and inflammation-associated proteins in Parkinson's disease patients and controls., PMID:24586351
Immunolocalization of WNK4 in mouse kidney., PMID:21660484
Molecular signature of mice T lymphocytes following tolerance induction by allogeneic BMT and CD40-CD40L costimulation blockade., PMID:16441364
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)., PMID:12386165
For research use only. Not for human or drug use.
