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Anti-HDAC8 Antibody (R2K06)

Catalog #:   RHJ51303 Specific References (13) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, IHC, IP, WB
Accession: Q9BY41
Overview

Catalog No.

RHJ51303

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000

Target

HDAC8, Histone deacetylase 8, HD8, HDACL1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9BY41

Applications

FCM, IF, IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2K06

Data Image
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of HDAC8 expression in HeLa cell lysate.
References

Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the "Smart" exosome nanoparticle therapy., PMID:39004737

Histone deacetylase 8 inhibition suppresses mantle cell lymphoma viability while preserving natural killer cell function., PMID:33190829

HDAC8 inhibition ameliorates pulmonary fibrosis., PMID:30358439

Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells., PMID:29174371

Analysis of the interactome of Schistosoma mansoni histone deacetylase 8., PMID:29155817

HDAC inhibitors enhance the immunotherapy response of melanoma cells., PMID:29137331

Histone deacetylase inhibitors attenuate P-aIgA1-induced cell proliferation and extracellular matrix synthesis in human renal mesangial cells in vitro., PMID:26775659

Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo., PMID:25451941

Histone deacetylase 8 suppresses osteogenic differentiation of bone marrow stromal cells by inhibiting histone H3K9 acetylation and RUNX2 activity., PMID:25019367

Histone deacetylase 8 regulates cortactin deacetylation and contraction in smooth muscle tissues., PMID:24920679

Characterization of an antibody panel for immunohistochemical analysis of canine muscle cells., PMID:18617272

Novel smooth muscle markers reveal abnormalities of the intestinal musculature in severe colorectal motility disorders., PMID:16771768

Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells., PMID:15590418

Datasheet

Document Download

Anti-HDAC8 Antibody (R2K06).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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For research use only. Not for human or drug use.

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Anti-HDAC8 Antibody (R2K06) [RHJ51303]
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