Catalog No.
YHC94301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala24-Arg408
Predicted molecular weight
46.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12644
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BMP2B, BMP-2B, DVR4, Bone morphogenetic protein 4, BMP-4, BMP4, Bone morphogenetic protein 2B
Developmental trajectory and evolutionary origin of thymic mimetic cells., PMID:40500437
Signaling Centers Drive Brachyury Dynamics and Lineage Commitment in mESC Aggregates., PMID:40496355
Regeneration alters open chromatin and cis-regulatory landscape of erythroid precursors., PMID:40456602
Porphyromonas gingivalis induced DNA oxidative stress damage by iron overload to deplete CTCF expression and prevent osteogenic differentiation of periodontal ligament stem cells., PMID:40455363
Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice., PMID:40439112
miR-181a-5p mediates the effects of BMP4 on intestinal cell proliferation and differentiation., PMID:40436833
Opposing effects between retinoic acid and Fibroblast growth factor in patterning the common crus and semicircular canals of the inner ear., PMID:40436241
Influence of Unidirectional Vacuum Application on Bone Healing in Maxillofacial Surgery., PMID:40422254
Characterization of fibroblast-like synoviocytes from the synovial fluid of patients affected by juvenile idiopathic arthritis., PMID:40408229
Adaptive evolution of BMP4 as a potential mechanism for flipper forelimb changes in cetaceans., PMID:40407132
Targeting BMPER as a therapeutic strategy for pulmonary arterial hypertension., PMID:40383173
The critical role of BMP signaling in gastric epithelial cell differentiation revealed by organoids., PMID:40377813
A Cartilaginous Organoid System Derived From Human Expanded Pluripotent Stem Cells (hEPSCs)., PMID:40364989
p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics., PMID:40362216
Naringin Mitigates Chondrocyte Apoptosis in Osteoarthritis by Suppressing the miR-29a-3p-Bax Pathway., PMID:40358971
Effect of Recombinant Human Amelogenin on the Osteogenic Differentiation Potential of SHED., PMID:40358181
Hormonal regulation and expression dynamics of Bmp4 in the reproductive cycle of Pampus argenteus., PMID:40351264
Modulation of adipose tissue phenotype and longevity-related gene expression by nuclear factor E2-related factor 2 knockdown in 3T3-L1 cells., PMID:40341662
OTX2 expression contributes progression of gastric cancer in young adults., PMID:40341176
Distinct signalling dynamics of BMP4 and BMP9 in brown versus white adipocytes., PMID:40335635
Beige Adipocytes Promote Triple-Negative Breast Cancer Cell Migration and Malignancy Through BMP4 Signaling., PMID:40331744
The Impact Of Modern Industrialized Dietary Sodium Intake On The Plasma Proteome., PMID:40327765
BMP and WNT signaling are involved in tracheal cartilage development in chicken embryos., PMID:40324741
Low-Intensity Pulsed Ultrasound Promotes Osteogenesis in Porous Titanium Alloys Through miR-1187/BMP4 Pathway., PMID:40317956
Not all dimers are equal., PMID:40314998
Derivation of Mesenchymal Stem Cells through Sequential Presentation of Growth Factors via Gelatin Microparticles in Pluripotent Stem Cell Spheroids., PMID:40303481
Intestinal mucosal transcriptomic responses of Asian seabass (Lates calcarifer) vaccinated with an oral hydrogel-encapsulated multivalent Vibrio antigen following Vibrio spp. infection., PMID:40252617
Administration of Noggin Suppresses Fibrinogen Leakage into the Brain in the Acute Phase After Traumatic Brain Injury in Mice., PMID:40243640
Berberine Derivative Compound 13 as a Potent Promoter of Osteoblast Differentiation via Akt and PKC Signaling Pathways., PMID:40243591
The dominant negative mutation of PAX9 in nonsyndromic tooth agenesis., PMID:40227334
Human Fibroblast Growth Factor 9 Induces Hair Follicle Cycle Transition via TGF-β/BMP/Smad Pathway., PMID:40225311
HAND1, partially mediated through ape-specific LTR binding, is essential for human extra-embryonic mesenchyme derivation from iPSCs., PMID:40220298
The sonic hedgehog signaling inhibitor cyclopamine improves pulmonary arterial hypertension via regulating the bone morphogenetic protein receptor 2 pathway., PMID:40216933
Study on the common mechanisms of gastroesophageal reflux disease and interstitial lung disease., PMID:40209518
Improving in vitro induction efficiency of human primordial germ cell-like cells using N2B27 or NAC-based medium., PMID:40204653
Melatonin mediates the BMP4/MAPK signaling pathway to alleviate zearalenone-induced abnormal embryonic development in mice., PMID:40120487
Targeting BMP4 as a therapeutic strategy for neovascularization and fibrosis in age-related macular degeneration., PMID:40118134
Pilot Exploration of RGMa-BMP4 Signaling in Neutrophil Activation in NMOSD: Integrating Clinical and Molecular Insights., PMID:40087219
Inhibition of bone morphogenetic protein 4 alleviates angiotensin II-induced abdominal aortic aneurysm by reducing inflammation and endothelial-mesenchymal transition., PMID:40081251
miR-6402 targets Bmpr2 and negatively regulates mouse adipogenesis., PMID:40028748
Transcytosis of LDL Across Arterial Endothelium: Mechanisms and Therapeutic Targets., PMID:40013359
Propagation of goose primordial germ cells in vitro relies on FGF and BMP signalling pathways., PMID:40000797
Enhancing spermatogonial stem cell differentiation: The role of alpha-ketoglutarate in in-Vitro cultures., PMID:39970551
Deterministic Role of FOXF2 in Organ-Specific Macrometastasis Transition., PMID:39957349
Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene., PMID:39947597
Altered Sertoli Cell Function Contributes to Spermatogenic Arrest in Dogs with Chronic Asymptomatic Orchitis., PMID:39940876
Non-Canonical Wnt16 and microRNA-145 Mediate the Response of Human Bone Marrow Stromal Cells to Additively Manufactured Porous 3-Dimensional Biomimetic Titanium-Aluminum-Vanadium Constructs., PMID:39937002
High-Density Lipoproteins from Coronary Artery Disease and Aortic Valve Stenosis Patients Differentially Regulate Gene Expression in a Model of Cardiac Adipocytes., PMID:39936996
The Hedgehog-GLI1 Pathway Regulates Osteogenic Differentiation of Human Cervical Posterior Longitudinal Ligament Cells by BMP Signalling Pathway., PMID:39910703
Therapeutic inhibition of PHF21B attenuates pathological cardiac hypertrophy by inhibiting the BMP4/GSK3β/β-catenin axis., PMID:39900327
For research use only. Not for human or drug use.
