Catalog No.
YHC92401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln26-Val214
Predicted molecular weight
22.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12111
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen alpha-3(VI) chain, COL6A3
A diet-driven metabolic dysfunction-associated steatohepatitis (MASH) mouse model resembles the corresponding human disease., PMID:40392411
Collagen type VI regulates TGF-β bioavailability in skeletal muscle in mice., PMID:40309777
Altered expression of collagen gene family members and its epigenetic background in equine Sarcoids., PMID:40288239
Clinical, Pathologic, and Genetic Spectrum of Collagen VI-Related Disorder in China-A Retrospective Observational Multicenter Study., PMID:40225934
Lysyl hydroxylase 2 glucosylates collagen VI to drive lung cancer progression., PMID:40166934
Identification of Candidate Lung Function-Related Plasma Proteins to Pinpoint Drug Targets for Common Pulmonary Diseases: A Comprehensive Multi-Omics Integration Analysis., PMID:40136421
The potential key genes within focal adhesion that regulate mesenchymal stem cells osteogenesis or adipogenesis in microgravity related disuse osteoporosis: an integrated analysis., PMID:40130165
Fibrosis-Related Gene and Protein Expression in Normal and Glaucomatous Trabecular Meshwork Cells., PMID:40126508
Single nucleotide polymorphisms in ovarian cancer impacting lipid metabolism and prognosis: an integrated TCGA database analysis., PMID:40082829
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis., PMID:40026415
Roles of WDR12 and MRTO4 genes in colorectal cancer., PMID:39969382
Key RNA-binding proteins in renal fibrosis: a comprehensive bioinformatics and machine learning framework for diagnostic and therapeutic insights., PMID:39957043
Proteome-Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm., PMID:39895541
Depot-specific acetylation profiles of adipose tissues-therapeutic targets for metabolically unhealthy obesity., PMID:39881347
Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease., PMID:39856218
Comparative transcriptome analysis of albino northern snakehead (Channa argus) reveals its various collagen-related DEGs in caudal fin cells., PMID:39739744
FBLN1 regulates ferroptosis in acute respiratory distress syndrome by reducing free ferrous iron by inhibiting the TGF-β/Smad pathway., PMID:39671383
Identification and validation of cigarette smoking-related genes in predicting prostate cancer development through bioinformatic analysis and experiments., PMID:39625524
Segregation of the COL6A2 Variant (c.1817-3C>G) in a Consanguineous Saudi Family with Bethlem Myopathy., PMID:39596604
Restored Collagen VI Microfilaments Network in the Extracellular Matrix of CRISPR-Edited Ullrich Congenital Muscular Dystrophy Fibroblasts., PMID:39595588
Citrullinated and malondialdehyde-acetaldehyde-modified fibrinogen activates macrophages and promotes profibrotic responses in human lung fibroblasts., PMID:39560968
Single-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma., PMID:39548577
A Novel Splice Site Variant in COL6A1 Causes Ullrich Congenital Muscular Dystrophy in a Consanguineous Malian Family., PMID:39523858
Identification of SNPs and INDELS associated with duck egg quality traits through a genome-wide association analysis., PMID:39504828
Identification of hub genes through integrated single-cell and microarray transcriptome analysis in osteoarthritic meniscus., PMID:39438957
Plasma proteomics reveals the potential causal impact of extracellular matrix proteins on abdominal aortic aneurysm., PMID:39398994
Mutations in COL6A Gene Family Responsible for Muscular Dystrophies in Three Unrelated Families., PMID:39397694
Changes of collagen content in lung tissues of plateau yak and its mechanism of adaptation to hypoxia., PMID:39372716
Distinct muscle regenerative capacity of human induced pluripotent stem cell-derived mesenchymal stromal cells in Ullrich congenital muscular dystrophy model mice., PMID:39370505
Clinical and Molecular Profiles of a Cohort of Egyptian Patients with Collagen VI-Related Dystrophy., PMID:39367186
Mapping biological influences on the human plasma proteome beyond the genome., PMID:39327534
Expert panel curation of 31 genes in relation to limb girdle muscular dystrophy., PMID:39215466
COL6A3 Exosomes Promote Tumor Dissemination and Metastasis in Epithelial Ovarian Cancer., PMID:39125689
Targeted panel sequencing of pharmacogenes and oncodrivers in colorectal cancer patients reveals genes with prognostic significance., PMID:39030589
A Damaging COL6A3 Variant Alters the MIR31HG-Regulated Response of Chondrocytes in Neocartilage Organoids to Hyperphysiologic Mechanical Loading., PMID:39021299
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
Constructing networks for comparison of collagen types., PMID:38997817
Instrumental variable and colocalization analyses identify endotrophin and HTRA1 as potential therapeutic targets for coronary artery disease., PMID:38989470
Avellanin A Has an Antiproliferative Effect on TP-Induced RWPE-1 Cells via the PI3K-Akt Signalling Pathway., PMID:38921586
Identification of key modules and hub genes involved in regulating the feather follicle development of Wannan chickens using WGCNA., PMID:38908121
Identification of potential shared gene signatures between gastric cancer and type 2 diabetes: a data-driven analysis., PMID:38903804
Integrative analysis of COL6A3 in lupus nephritis: insights from single-cell transcriptomics and proteomics., PMID:38855105
Proteome-Wide Multicenter Mendelian Randomization Analysis to Identify Novel Therapeutic Targets for Lung Cancer., PMID:38824092
Proteomic profile of tissue-derived extracellular vesicles from benign odontogenic lesions., PMID:38795909
Genome-wide identification and analysis of epithelial-mesenchymal transition-related RNA-binding proteins and alternative splicing in a human breast cancer cell line., PMID:38783078
Identification of novel variations in three cases with rare inherited neuromuscular disorder., PMID:38756899
Plasma proteomic biomarkers and the association between poor cardiovascular health and incident dementia: The UK Biobank study., PMID:38710337
[Screening of differentially expressed genes in gastric cancer based on GEO database and function and pathway enrichment analysis]., PMID:38597453
System biology approaches to identify hub genes linked with ECM organization and inflammatory signaling pathways in schizophrenia pathogenesis., PMID:38322840
COL6A3 enhances the osteogenic differentiation potential of BMSCs by promoting mitophagy in the osteoporotic microenvironment., PMID:38270688
For research use only. Not for human or drug use.
