Catalog No.
YHC92201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn770-Gly1028
Predicted molecular weight
30.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12109
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COL6A1, Collagen alpha-1(VI) chain
Acquired resistance to immunotherapy by physical barriers with cancer cell-expressing collagens in non-small cell lung cancer., PMID:40498460
Genetic Determinants of Colonic Diverticulosis-A Systematic Review., PMID:40428403
RNA sequencing and genome-wide association analysis reveal key genes responsible for different feather colors in Youjiang goose., PMID:40424883
Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs., PMID:40329180
Collagen type VI regulates TGF-β bioavailability in skeletal muscle in mice., PMID:40309777
Predicting Prognosis and Immunotherapy Response in Glioblastoma (GBM) With a 5-Gene CAF-Risk Signature., PMID:40226936
Clinical, Pathologic, and Genetic Spectrum of Collagen VI-Related Disorder in China-A Retrospective Observational Multicenter Study., PMID:40225934
Mechanistic study of COL6A1-mediated subchondral bone remodeling in osteoarthritis via the EPAC/RAP1 axis., PMID:40143596
COL6A1 Promotes Milk Production and Fat Synthesis Through the PI3K-Akt/Insulin/AMPK/PPAR Signaling Pathways in Dairy Cattle., PMID:40076877
Proteomic profiling of kars knockout zebrafish larvae., PMID:40032059
Identification of potential genes associated with metastasis in osteosarcoma: an integrated bioinformatics analysis., PMID:40000579
circ0066187 promotes pulmonary fibrogenesis through targeting STAT3-mediated metabolism signal pathway., PMID:39969586
Generation of an iPSC line (with isogenic control) from the PBMCs of a COL6A1 (c.1056 + 2T > A) Bethlem myopathy patient., PMID:39954549
Differentiation of human hyalocytes from induced pluripotent stem cells through ascorbic acid treatment., PMID:39937308
Confusing Histopathological Features and HPV Testing Results in Vulvar Squamous Cell Carcinoma Arising in a Young Woman: A Case Solved Using Next-Generation Sequencing., PMID:39928484
TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep., PMID:39913466
Depot-specific acetylation profiles of adipose tissues-therapeutic targets for metabolically unhealthy obesity., PMID:39881347
Suppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches., PMID:39797986
Generation of a human induced pluripotent stem cell line (CRICKi021-A) from a patient with Ullrich congenital muscular dystrophy carrying a pathogenic mutation in the COL6A1 gene., PMID:39764974
Comparative transcriptome analysis of albino northern snakehead (Channa argus) reveals its various collagen-related DEGs in caudal fin cells., PMID:39739744
Segregation of the COL6A2 Variant (c.1817-3C>G) in a Consanguineous Saudi Family with Bethlem Myopathy., PMID:39596604
Restored Collagen VI Microfilaments Network in the Extracellular Matrix of CRISPR-Edited Ullrich Congenital Muscular Dystrophy Fibroblasts., PMID:39595588
Analysis of candidate variants in a Chinese family with monozygotic twins with keratoconus: a case report., PMID:39544142
A Novel Splice Site Variant in COL6A1 Causes Ullrich Congenital Muscular Dystrophy in a Consanguineous Malian Family., PMID:39523858
Proteomic Characterization of Corneal Epithelial and Stromal Cell-Derived Extracellular Vesicles., PMID:39408670
Mutations in COL6A Gene Family Responsible for Muscular Dystrophies in Three Unrelated Families., PMID:39397694
Changes of collagen content in lung tissues of plateau yak and its mechanism of adaptation to hypoxia., PMID:39372716
Distinct muscle regenerative capacity of human induced pluripotent stem cell-derived mesenchymal stromal cells in Ullrich congenital muscular dystrophy model mice., PMID:39370505
Clinical and Molecular Profiles of a Cohort of Egyptian Patients with Collagen VI-Related Dystrophy., PMID:39367186
COL6A1 Inhibits the Malignant Development of Bladder Cancer by Regulating FBN1., PMID:39365515
Combining Transcriptomics and Proteomics to Screen Candidate Genes Related to Bovine Birth Weight., PMID:39335340
Low-Dose Metformin and Profibrotic Signature in Central Centrifugal Cicatricial Alopecia., PMID:39230880
Expert panel curation of 31 genes in relation to limb girdle muscular dystrophy., PMID:39215466
Machine learning and 4D-LFQ quantitative proteomic analysis explore the molecular mechanism of kidney stone formation., PMID:39114033
Phenotype-genotype spectrum of a cohort of congenital muscular dystrophies: a single-centre experience from India., PMID:39103709
Anti-photoaging effect and the mechanism of Coreopsis tinctoria okanin against UVB-induced skin damage in mice., PMID:39024749
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
Salbutamol repurposing ameliorates neuromuscular junction defects and muscle atrophy in Col6a1-/- mouse model of collagen VI-related myopathies., PMID:38984773
The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease., PMID:38915286
Identification and validation of COL6A1 as a novel target for tumor electric field therapy in glioblastoma., PMID:38887185
Proteomic profile of tissue-derived extracellular vesicles from benign odontogenic lesions., PMID:38795909
Identification of established and novel extracellular matrix components in glioblastoma as targets for angiogenesis and prognosis., PMID:38775886
A Mild But Typical Presentation of Bethlem Myopathy With a Novel In-Frame Deletion in COL6A1: Almost Overlooked., PMID:38754040
Exome sequencing in extreme altitude mountaineers identifies pathogenic variants in RTEL1 and COL6A1 previously associated with respiratory failure., PMID:38653581
Identification of hub genes and key pathways in spinal cord injury via bioinformatics analysis., PMID:38650155
Analyses of lncRNA and mRNA profiles in recurrent atrial fibrillation after catheter ablation., PMID:38643140
Gadolinium retention effect on macrophages - a potential cause of MRI contrast agent Dotarem toxicity., PMID:38625373
[Dynamic trajectory and cell communication of different cell clusters in malignant progression of glioblastoma]., PMID:38595234
A humanized knock-in Col6a1 mouse recapitulates a deep-intronic splice-activating variant., PMID:38585878
Identifying critical genes and pathways of doxorubicin-induced cardiomyopathy via bioinformatics analysis., PMID:38497849
For research use only. Not for human or drug use.
