Catalog No.
RHH32602
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
OCT-binding factor 1, POU domain class 2-associating factor 1, OBF1, POU2AF1, BOB1, OCA-B, BOB-1, B-cell-specific coactivator OBF-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q16633
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2H27
Identification of New Single Nucleotide Polymorphisms Potentially Related to Small Ruminant Lentivirus Infection Susceptibility in Goats Based on Data Selected from High-Throughput Sequencing., PMID:39452702
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Transcriptomic Analysis Reveals Sixteen Potential Genes Associated with the Successful Differentiation of Antibody-Secreting Cells through the Utilization of Unfolded Protein Response Mechanisms in Robust Responders to the Influenza Vaccine., PMID:38400120
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation., PMID:36685499
BOB.1 controls memory B-cell fate in the germinal center reaction., PMID:31053401
J chain and myocyte enhancer factor 2B are useful in differentiating classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma and primary mediastinal large B-cell lymphoma., PMID:28851661
High frequency of Bob1lo T follicular helper cells in florid reactive follicular hyperplasia., PMID:28756244
Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma., PMID:28064239
TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1., PMID:28053195
The Transcriptional Coactivator Bob1 Is Associated With Pathologic B Cell Responses in Autoimmune Tissue Inflammation., PMID:27907250
Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response., PMID:25238757
MiR-126: a novel route for natalizumab action?, PMID:24598267
IgM autoantibodies: Roquin and Bob1ng to a different tune., PMID:24217813
Germinal center-independent, IgM-mediated autoimmunity in sanroque mice lacking Obf1., PMID:24217807
B-cell transcription factor expression and immunoglobulin gene rearrangement frequency in acute myeloid leukemia with t(8;21)(q22;q22)., PMID:23955454
B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1., PMID:23045607
Direct interactions of OCA-B and TFII-I regulate immunoglobulin heavy-chain gene transcription by facilitating enhancer-promoter communication., PMID:21549311
BOB.1, CD79a and cyclin E are the most appropriate markers to discriminate classical Hodgkin's lymphoma from primary mediastinal large B-cell lymphoma., PMID:20102401
Early signal protein expression profiles in basophils: a population study., PMID:19436043
Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1., PMID:18974788
Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells., PMID:18695675
B cell response is required for granuloma formation in the early infection of Schistosoma japonicum., PMID:18320044
Two levels of protection for the B cell genome during somatic hypermutation., PMID:18273020
Identification of ERdj3 and OBF-1/BOB-1/OCA-B as direct targets of XBP-1 during plasma cell differentiation., PMID:17709512
Hodgkin-like anaplastic large cell lymphoma (previously designated in the REAL classification) has same immunophenotypic features to classical Hodgkin lymphoma., PMID:17577776
OBF-1 is essential for the generation of antibody-secreting cells and the development of autoimmunity in MRL-lpr mice., PMID:17574818
B29 gene silencing in pituitary cells is regulated by its 3' enhancer., PMID:16920149
The Ets factor Spi-B is a direct critical target of the coactivator OBF-1., PMID:16861304
Expression of B-cell transcription factors in primary cutaneous B-cell lymphoma., PMID:16778825
Nontranscriptional regulation of SYK by the coactivator OCA-B is required at multiple stages of B cell development., PMID:16713566
Expression profiling of transcription factors Pax-5, Oct-1, Oct-2, BOB.1, and PU.1 in Hodgkin's and non-Hodgkin's lymphomas: a comparative study using high throughput tissue microarrays., PMID:16648862
Rap1 signal controls B cell receptor repertoire and generation of self-reactive B1a cells., PMID:16618600
Interaction of the B cell-specific transcriptional coactivator OCA-B and galectin-1 and a possible role in regulating BCR-mediated B cell proliferation., PMID:16565088
Expression of immunoglobulin transcription factors in primary intraocular lymphoma and primary central nervous system lymphoma., PMID:16249468
Differential requirement for OBF-1 during antibody-secreting cell differentiation., PMID:15867091
Alterations of loci encoding PU.1, BOB1, and OCT2 transcription regulators do not correlate with their suppressed expression in Hodgkin lymphoma., PMID:15796964
Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia., PMID:15672409
Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression., PMID:15284123
Analysis of transcription factor OCT.1, OCT.2 and BOB.1 expression using tissue arrays in classical Hodgkin's lymphoma., PMID:15257313
The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination., PMID:15252056
CD86 and beta2-adrenergic receptor signaling pathways, respectively, increase Oct-2 and OCA-B Expression and binding to the 3'-IgH enhancer in B cells., PMID:15024018
Differential Emu enhancer activity and expression of BOB.1/OBF.1, Oct2, PU.1, and immunoglobulin in reactive B-cell populations, B-cell non-Hodgkin lymphomas, and Hodgkin lymphomas., PMID:14694522
Critical role for the Oct-2/OCA-B partnership in Ig-secreting cells., PMID:14662861
The B-cell transcription factors BSAP, Oct-2, and BOB.1 and the pan-B-cell markers CD20, CD22, and CD79a are useful in the differential diagnosis of classic Hodgkin lymphoma., PMID:14608905
OCA-B regulation of B-cell development and function., PMID:14552839
OcaB regulates transitional B cell selection., PMID:12917262
Identification of transcription coactivator OCA-B-dependent genes involved in antigen-dependent B cell differentiation by cDNA array analyses., PMID:12857960
Disruption of the B-cell specific transcriptional program in HHV-8 associated primary effusion lymphoma cell lines., PMID:12592383
Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice., PMID:12574333
Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins., PMID:12507907
For research use only. Not for human or drug use.
