Catalog No.
YHC92101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp1564-Gly1806
Predicted molecular weight
29.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12107
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COL11A1, Collagen alpha-1(XI) chain, COLL6
ADAMTS5 Modulates Breast Cancer Development as a Diagnostic Biomarker and Potential Tumour Suppressor, Regulated by BAIAP2-AS1, CRNDE and hsa-miR-135b-3p: Integrated Systems Biology and Experimental Approach., PMID:40472834
Gene expression profiling of extraocular muscles in primary inferior oblique overaction., PMID:40452936
Altered expression of collagen gene family members and its epigenetic background in equine Sarcoids., PMID:40288239
Whole-exome sequencing screening for candidate genes and potential pathogenic variants associated with early-onset high myopia in 47 Chinese families., PMID:40175531
Transitional CXCL14+ cancer-associated fibroblasts enhance tumour metastasis and confer resistance to EGFR-TKIs, revealing therapeutic vulnerability to filgotinib in lung adenocarcinoma., PMID:40162549
Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population., PMID:40131712
ITGA8 deficiency in hepatic stellate cells attenuates CCl4-Induced liver fibrosis via suppression of COL11A1., PMID:40056500
Molecular subtyping of stage I lung adenocarcinoma via molecular alterations in pre-invasive lesion progression., PMID:40038757
SPP1hi macrophages, NKG7 T cells, CCL5hi fibroblasts, and IgM plasma cells are dominant features of necrobiosis., PMID:39989459
A cross-sectional study on the assessment of COLL11A1, VEGF, and GDF5 gene polymorphisms in Turkish patients with primary knee osteoarthritis., PMID:39953483
Ocular Biometry and Genomic Association in Primary Angle Closure Disease. A Descriptive study., PMID:39936063
The FUS/COL11A1/ZEB1 Axis Contributes to the Development of Oral Squamous Cell Carcinoma., PMID:39915978
Differential gene expression analysis and machine learning identified structural, TFs, cytokine and glycoproteins, including SOX2, TOP2A, SPP1, COL1A1, and TIMP1 as potential drivers of lung cancer., PMID:39888730
The Dynamic Changes of COL11A1 Expression During the Carcinogenesis and Development of Breast Cancer and as a Candidate Diagnostic and Prognostic Marker., PMID:39845732
Genome sequencing reveals novel variants in a diverse population with congenital anterior segment anomalies., PMID:39747279
The effects of different doses of compound enzyme preparations on the production performance, meat quality and rumen microorganisms of yak were studied by metagenomics and transcriptomics., PMID:39726957
Heterogeneous Group of Genetically Determined Auditory Neuropathy Spectrum Disorders., PMID:39684270
Effect of COL11A1 on oral squamous cell carcinoma., PMID:39631528
Fibroblast Activation Protein-α Expression in Cancer-Associated Fibroblasts Shows the Poor Survival of Colorectal Cancer via Immune-Mediated Pathways : Implications of FAP in Cancer-Associated Fibroblasts Link Immune Dysregulation to Adverse Survival in Colorectal Cancer., PMID:39623187
Tendon-targeted knockout of collagen XI disrupts patellar and Achilles tendon structure and mechanical properties during murine postnatal development., PMID:39620714
A meta-analysis of the effects of early life stress on the prefrontal cortex transcriptome suggests long-term effects on myelin., PMID:39605735
Phenotypic and Genetic Spectrum in 309 Consecutive Pediatric Patients with Inherited Retinal Disease., PMID:39596324
Innovative pan-tumor target strategy for CAR-T therapy: cancer-specific exons as novel targets for pediatric solid and brain tumors., PMID:39533264
Retinal detachment in Type IX collagen recessive Stickler syndrome., PMID:39406934
Pathobiology of the crystalline lens in Stickler syndrome., PMID:39349161
Inherited Variants in the COL11A, COL1A, COL5A1, COMP, GSTM1 Genes and the Risk of Carpal Tunnel Syndrome., PMID:39333034
Regulatory Role of Collagen XI in the Establishment of Mechanical Properties of Tendons and Ligaments in Mice Is Tissue Dependent., PMID:39297758
Integrated single-cell and bulk RNA sequencing identifies POSTN as a potential biomarker and therapeutic target for rheumatoid arthritis., PMID:39067546
Mutational and transcriptional profile predicts the prognosis of stage IV gastric cancer - Prognostic factors for metastatic gastric cancer., PMID:39043541
Molecular pathogenesis of microsatellite instability-high early-stage colorectal adenocarcinoma in India., PMID:39042905
Coenzyme Q-10 reduced the aberrant production of extracellular matrix proteins in uterine leiomyomas through transforming growth factor beta 3., PMID:39004304
Investigation of single nucleotide polymorphisms in differentially expressed genes and proteins reveals the genetic basis of skeletal muscle growth differences between Tibetan and Large White pigs., PMID:38938033
POLM variant G312R promotes ovarian tumorigenesis through genomic instability and COL11A1-NF-κB axis., PMID:38826139
Unlocking cellular plasticity: enhancing human iPSC reprogramming through bromodomain inhibition and extracellular matrix gene expression regulation., PMID:38825983
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression., PMID:38702309
[Prenatal phenotype and genetic analysis of a fetus with Fibrochondrogenesis 1 due to compound heterozygous variants of COL11A1 gene]., PMID:38684309
Clinical and Molecular Characterization of a Novel Homozygous Frameshift Variant in AEBP1-Related Classical-like Ehlers Danlos Syndrome Type 2 with Comparison to Previously Reported Rare Cases., PMID:38674395
Analysis of cancer-associated fibroblasts related genes identifies COL11A1 associated with lung adenocarcinoma prognosis., PMID:38649961
Integrated bioinformatics analysis reveals upregulated extracellular matrix hub genes in pancreatic cancer: Implications for diagnosis, prognosis, immune infiltration, and therapeutic strategies., PMID:38639039
[Features of genetic mutations in children with high myopia combined with peripheral retinal degenerations]., PMID:38450462
Transcriptome Analysis Identifies Tumor Immune Microenvironment Signaling Networks Supporting Metastatic Castration-Resistant Prostate Cancer., PMID:38435029
Microphthalmia and congenital cataract in two patients with Stickler syndrome type II: a case report., PMID:38299479
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis., PMID:38277211
Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression., PMID:38260279
Mesenteric fibrosis in patients with small intestinal neuroendocrine tumors is associated with enrichment of alpha-smooth muscle actin-positive fibrosis and COMP-expressing stromal cells., PMID:38246597
Clinical and genetic risk factors underlying severe consequence identified in 75 families with unilateral high myopia., PMID:38243264
Screening for Biomarkers Related to Pigmentation and Formation in Vitiligo., PMID:38231049
Multiocular defect in the Old English Sheepdog: A canine form of Stickler syndrome type II associated with a missense variant in the collagen-type gene COL11A1., PMID:38153936
Inhibition of miR-199a-3p in a murine hypertrophic cardiomyopathy (HCM) model attenuates fibrotic remodeling., PMID:38143961
Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancer., PMID:38066539
For research use only. Not for human or drug use.
