Catalog No.
RHG61201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:500-1:1000
Target
Cullin-1, CUL-1, CUL1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13616
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2E77
Omics data integration analysis identified new biological insights into chronic antibody-mediated rejection (CAMR)., PMID:39979925
Activity-based profiling of cullin-RING E3 networks by conformation-specific probes., PMID:37653169
Activity-based profiling of cullin-RING ligase networks by conformation-specific probes., PMID:36711970
CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma., PMID:33428680
Antibody-free detection of cellular neddylation dynamics of Cullin1., PMID:29733811
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors., PMID:26474281
Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets., PMID:26108621
SOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties., PMID:25632159
Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function., PMID:23110726
The ORF2 glycoprotein of hepatitis E virus inhibits cellular NF-κB activity by blocking ubiquitination mediated proteasomal degradation of IκBα in human hepatoma cells., PMID:22590978
Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress., PMID:21205095
Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation., PMID:20154143
Expression of calcyclin-binding protein/Siah-1 interacting protein in normal and malignant human tissues: an immunohistochemical survey., PMID:18443365
FBXO25-associated nuclear domains: a novel subnuclear structure., PMID:18287534
Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles., PMID:15511225
Severely impaired B lymphocyte proliferation, survival, and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background., PMID:14764675
The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1., PMID:11967155
In vitro ubiquitination of cyclin D1 by ROC1-CUL1 and ROC1-CUL3., PMID:11311237
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1., PMID:11027288
Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle., PMID:10485847
Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway., PMID:9430629
For research use only. Not for human or drug use.
