Catalog No.
RHG53602
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Disintegrin and metalloproteinase domain-containing protein 15, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, ADAM15, MDC15, Metalloprotease RGD disintegrin protein, Metargidin, MDC-15, ADAM 15
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13444
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2E35
Proteome-wide mendelian randomization identifies causal plasma proteins in interstitial lung disease., PMID:39824903
Characterization of circulating tumor cells in patients with metastatic bladder cancer utilizing functionalized microfluidics., PMID:39173508
Correction: Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis., PMID:36316756
Endothelin 1, NF-κB, and ADAM-15 expression in diabetic foot wounds., PMID:30685994
ADAM15 in Apoptosis Resistance of Synovial Fibroblasts: Converting Fas/CD95 Death Signals Into the Activation of Prosurvival Pathways by Calmodulin Recruitment., PMID:30003689
MPDU1 regulates CEACAM1 and cell adhesion in vitro and in vivo., PMID:29671116
Peptide Binding Glucose Regulated Protein 78 Improves Type 1 Diabetes by Preventing Pancreatic β Cell Apoptosis., PMID:27123783
ADAM15 participates in fertilization through a physical interaction with acrogranin., PMID:25392190
EGF promotes the shedding of soluble E-cadherin in an ADAM10-dependent manner in prostate epithelial cells., PMID:22024284
ADAM15 to α5β1 integrin switch in colon carcinoma cells: a late event in cancer progression associated with tumor dedifferentiation and poor prognosis., PMID:21190186
ADAM33 expression in atherosclerotic lesions and relationship of ADAM33 gene variation with atherosclerosis., PMID:20227692
ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis., PMID:20213810
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability., PMID:19308291
Presence, processing, and localization of mouse ADAM15 during sperm maturation and the role of its disintegrin domain during sperm-egg binding., PMID:18390692
Inhibition of airway smooth muscle adhesion and migration by the disintegrin domain of ADAM-15., PMID:17575078
ADAM-15/metargidin mediates homotypic aggregation of human T lymphocytes and heterotypic interactions of T lymphocytes with intestinal epithelial cells., PMID:17416588
Clustering of pre-B cell integrins induces galectin-1-dependent pre-B cell receptor relocalization and activation., PMID:16818733
Novel function of human ADAM15 disintegrin-like domain and its derivatives in platelet aggregation., PMID:16797059
Expression of ADAM15 in lung carcinomas., PMID:15756594
The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer., PMID:15586220
Increased expression of ADAM family members in human breast cancer and breast cancer cell lines., PMID:15565459
Chronological gene expression of ADAMs during testicular development: prespermatogonia (gonocytes) express fertilin beta (ADAM2)., PMID:12815633
The role of ADAM 15 in glomerular mesangial cell migration., PMID:12091380
Highly enhanced expression of the disintegrin metalloproteinase MDC15 (metargidin) in rheumatoid synovial tissue., PMID:11592366
RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction., PMID:10944520
Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells., PMID:9914169
Intracellular maturation of the mouse metalloprotease disintegrin MDC15., PMID:9748307
Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence., PMID:8617717
For research use only. Not for human or drug use.
