Catalog No.
YHC86401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu31-Asn341
Predicted molecular weight
36.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11177
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PDHB, PDHE1-B, PHE1B, Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Bioinformatics-led identification of pathophysiological hallmark genes in diabesotension via graph clustering method., PMID:40491693
Cobalt-induced stress reveals a prominent role of CzcC on the proteomic profile of Gluconacetobacter diazotrophicus PAL5., PMID:40402853
Multi-Omics Integration Reveals Mitochondrial Gene Regulation as a Determinant of Tuberculosis Susceptibility: A Mendelian Randomization Approach., PMID:40149725
PER2 interaction with HSP70 promotes cuproptosis in oral squamous carcinoma cells by decreasing AKT stability., PMID:40113747
Activation of PI3K-AKT pathway prevents steroid-induced osteonecrosis of the femoral head via inhibiting Cuproptosis., PMID:40089548
A missense mutation in PDHB gene: identification of the patient with pyruvate dehydrogenase deficiency and demonstration of pathogenicity in vitro., PMID:40050878
The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome., PMID:39810946
Role of immune-related endoplasmic reticulum stress genes in sepsis-induced cardiomyopathy: Novel insights from bioinformatics analysis., PMID:39671358
Mechanism of jianxin granules in the treatment of heart failure based on proteomics and metabolomics., PMID:39605071
Comprehensive analysis of the expression level, prognostic value, and immune infiltration of cuproptosis-related genes in human breast cancer., PMID:39432636
Identification of cuproptosis-related genes in Alzheimer's disease based on bioinformatic analysis., PMID:39396083
Identification of potential biomarkers of cuproptosis in cerebral ischemia., PMID:39360273
Risk factor prediction and immune correlation analysis of cuproptosis-related gene in osteoarthritis., PMID:39087591
Cuproptosis, the novel type of oxidation-induced cell death in thoracic cancers: can it enhance the success of immunotherapy?, PMID:39068453
Significance and Possible Biological Mechanism for CLDN8 Downregulation in Kidney Renal Clear Cell Carcinoma Tissues., PMID:38993257
Defective pgsA contributes to increased membrane fluidity and cell wall thickening in Staphylococcus aureus with high-level daptomycin resistance., PMID:38752757
Comprehensive bioinformatics analytics and in vivo validation reveal SLC31A1 as an emerging diagnostic biomarker for acute myocardial infarction., PMID:38713173
Identification of 10 differentially expressed and cuproptosis-related genes in immune infiltration and prognosis of thyroid carcinoma., PMID:38650151
Exploration of a Predictive Model for Keloid and Potential Therapeutic Drugs Based on Immune Infiltration and Cuproptosis-Related Genes., PMID:38334429
Analysis of the potential biological value of pyruvate dehydrogenase E1 subunit β in human cancer., PMID:38292838
Potential impact of cuproptosis-related genes on tumor immunity in esophageal carcinoma., PMID:38159255
[Identification and expression analysis of apple PDHB-1 gene family]., PMID:38147995
Comprehensive analysis of cuproptosis genes and cuproptosis-related genes as prognosis factors in esophageal squamous cell carcinoma., PMID:37866660
Identification of cuproptosis-related subtypes, characterization of immune microenvironment infiltration, and development of a prognosis model for osteoarthritis., PMID:37809099
Bioinformatics analysis of copper death gene in diabetic immune infiltration., PMID:37773841
Cuproptosis-Related 4-Gene Risk Model for Predicting Immunotherapy Drug Response and Prognosis of Kidney Renal Clear Cell Carcinoma., PMID:37503721
Comparative iTRAQ proteomics identified proteins in fresh and frozen thawed yak spermatozoa., PMID:37422242
Sargentodoxa cuneata and Patrinia villosa extract inhibits LPS-induced inflammation by shifting macrophages polarization through FAK/PI3K/Akt pathway regulation and glucose metabolism reprogramming., PMID:37390878
Integrated single-cell and bulk characterization of cuproptosis key regulator PDHB and association with tumor microenvironment infiltration in clear cell renal cell carcinoma., PMID:37350959
The genome of Candidatus phytoplasma ziziphi provides insights into their biological characteristics., PMID:37173622
Characterization of cuproptosis identified immune microenvironment and prognosis in acute myeloid leukemia., PMID:36826709
PDHB-AS suppresses cervical cancer progression and cisplatin resistance via inhibition on Wnt/β-catenin pathway., PMID:36750722
Leigh Syndrome: Spectrum of Molecular Defects and Clinical Features in Russia., PMID:36675121
Hcp1-loaded staphylococcal membrane vesicle vaccine protects against acute melioidosis., PMID:36618368
Bioinformatic Analysis of Genetic Factors from Human Blood Samples and Postmortem Brains in Parkinson's Disease., PMID:36593912
A novel fusion protein candidate for the serodiagnosis of Mycoplasma agalactiae infection., PMID:36581939
Pyruvate dehydrogenase B regulates myogenic differentiation via the FoxP1-Arih2 axis., PMID:36564038
Anisomycin has a potential toxicity of promoting cuproptosis in human ovarian cancer stem cells by attenuating YY1/lipoic acid pathway activation., PMID:36484005
A novel cuproptosis-related gene signature of prognosis and immune microenvironment in head and neck squamous cell carcinoma cancer., PMID:36376617
ERN1 dependent impact of glutamine and glucose deprivations on the pyruvate dehydrogenase genes expression in glioma cells., PMID:36270342
Reduced CircSMOC1 Level Promotes Metabolic Reprogramming via PTBP1 (Polypyrimidine Tract-Binding Protein) and miR-329-3p in Pulmonary Arterial Hypertension Rats., PMID:35997022
Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation., PMID:35889222
Isolated Paroxysmal Non-kinesigenic Dystonia Associated with Homozygous PDHB Variant in an Indian Family., PMID:35838632
A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma., PMID:35627236
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing., PMID:35618940
Identification of Prognostic Gene Biomarkers in Non-Small Cell Lung Cancer Progression by Integrated Bioinformatics Analysis., PMID:34827193
Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth., PMID:34749809
Lung branching morphogenesis is accompanied by temporal metabolic changes towards a glycolytic preference., PMID:34274010
For research use only. Not for human or drug use.
