Catalog No.
RHG35205
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
hDlg, Synapse-associated protein 97, SAP-97, Disks large homolog 1, DLG1, SAP97
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q12959
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2D61
Anoctamin 9 determines Ca2+ signals during activation of T-lymphocytes., PMID:40207216
Interplay between Netrin-1 and Norrin controls arteriovenous zonation of blood-retina barrier integrity., PMID:39693351
Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity., PMID:36711611
CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans., PMID:34849800
Scrib and Dlg1 polarity proteins regulate Ag presentation in human dendritic cells., PMID:32293058
Discs large homolog 1 regulates B-cell proliferation and antibody production., PMID:31169885
Dlg1 Maintains Dendritic Cell Function by Securing Voltage-Gated K+ Channel Integrity., PMID:31028120
A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large., PMID:27506200
Phosphoproteomic Analysis Using the WW and FHA Domains as Biological Filters., PMID:26119529
Detection of in situ protein-protein complexes at the Drosophila larval neuromuscular junction using proximity ligation assay., PMID:25650626
Angiotensin II upregulates Kv1.5 expression through ROS-dependent transforming growth factor-beta1 and extracellular signal-regulated kinase 1/2 signalings in neonatal rat atrial myocytes., PMID:25451261
Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg., PMID:25268382
Loss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signaling., PMID:24824078
DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis., PMID:24699546
Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg., PMID:24503895
Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity., PMID:23653213
SAP97 promotes the stability of Nax channels at the plasma membrane., PMID:23022437
The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors., PMID:22855505
Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex., PMID:21031555
A monoclonal antibody toolkit for C. elegans., PMID:20405020
Immunocytochemical localization of synaptic proteins to photoreceptor synapses of Drosophila melanogaster., PMID:20127822
An arginine stretch limits ADAM10 exit from the endoplasmic reticulum., PMID:20100836
The plasma membrane Ca(2+)-ATPase: regulation by PSD-95/Dlg/Zo-1 scaffolds., PMID:20100590
Analysis of the potential role of GluA4 carboxyl-terminus in PDZ interactions., PMID:20090852
Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis., PMID:19623611
The high-risk HPV E6 oncoprotein preferentially targets phosphorylated nuclear forms of hDlg., PMID:19307009
DLG1/SAP97 modulates transforming growth factor alpha bioavailability., PMID:18930083
Changes in localization of human discs large (hDlg) during keratinocyte differentiation are [corrected] associated with expression of alternatively spliced hDlg variants., PMID:17574238
Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity., PMID:17301176
Adenomatous polyposis coli (APC) protein regulates epithelial cell migration and morphogenesis via PDZ domain-based interactions with plasma membranes., PMID:17295841
The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1., PMID:17284442
Dual role of CaMKII-dependent SAP97 phosphorylation in mediating trafficking and insertion of NMDA receptor subunit NR2A., PMID:17156128
A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands., PMID:16825666
Localization of PDZ domain containing proteins Discs Large-1 and Scribble in the mouse eye., PMID:16402019
Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in Drosophila., PMID:15638945
Differential expression of human Dlg in cervical intraepithelial neoplasias., PMID:15099956
The apical disposition of the Caenorhabditis elegans intestinal terminal web is maintained by LET-413., PMID:15063180
Affinity purification of PSD-95-containing postsynaptic complexes., PMID:14622105
Association of a lung tumor suppressor TSLC1 with MPP3, a human homologue of Drosophila tumor suppressor Dlg., PMID:13679854
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism., PMID:12532395
Expression, regulation and role of the MAGUK protein SAP-97 in human atrial myocardium., PMID:12445884
Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias., PMID:12419826
Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors., PMID:12122038
Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses., PMID:11997254
Electron microscopic immunocytochemical detection of PSD-95, PSD-93, SAP-102, and SAP-97 at postsynaptic, presynaptic, and nonsynaptic sites of adult and neonatal rat visual cortex., PMID:11309840
Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97., PMID:11181181
SAP97 concentrates at the postsynaptic density in cerebral cortex., PMID:11029631
Ion channel clustering by membrane-associated guanylate kinases. Differential regulation by N-terminal lipid and metal binding motifs., PMID:10779526
Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding., PMID:10646847
Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer's disease., PMID:10588576
For research use only. Not for human or drug use.
