Catalog No.
RHF92501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
CENP-E, CENPE, Kinesin-related protein CENPE, Centromere-associated protein E, Centromere protein E, Kinesin-7
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q02224
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2C15
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
Targeting CENP-E augments immunotherapy in non-small cell lung cancer via stabilizing PD-L1., PMID:38043265
Functional Assessment of Kinesin-7 CENP-E in Spermatocytes using In Vivo Inhibition, Immunofluorescence and Flow Cytometry., PMID:35037651
Comparative Analysis on Abnormal Methylome of Differentially Expressed Genes and Disease Pathways in the Immune Cells of RA and SLE., PMID:34079550
Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules., PMID:25743205
Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin., PMID:24850177
Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors., PMID:24133140
Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes., PMID:22513372
Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases., PMID:21888900
Distribution of centromeric proteins and PARP-1 during mitosis and apoptosis., PMID:19723035
Chromosome congression in the absence of kinetochore fibres., PMID:19525938
Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes., PMID:18252055
Inhibition of protein kinase C zeta blocks the attachment of stable microtubules to kinetochores leading to abnormal chromosome alignment., PMID:16820280
CENP-F is a novel microtubule-binding protein that is essential for kinetochore attachments and affects the duration of the mitotic checkpoint delay., PMID:16601978
Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling., PMID:16144904
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores., PMID:15964272
Unstable Robertsonian translocations der(13;15)(q10;q10): heritable chromosome fission without phenotypic effect in two kindreds., PMID:15889410
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles., PMID:15458642
Human centromere repositioning "in progress"., PMID:15084747
Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1., PMID:12859900
Transient CENP-E-like kinetochore proteins in plants., PMID:12498345
Extensive cytogenetic analysis of a stable dicentric isochromosome 21, idic(21), formed by fusion of the terminal long arms., PMID:12438703
Anaphase onset does not require the microtubule-dependent depletion of kinetochore and centromere-binding proteins., PMID:12235289
Expression and behaviour of CENP-E at kinetochores during mouse spermatogenesis., PMID:12068923
The kinase activity of aurora B is required for kinetochore-microtubule interactions during mitosis., PMID:12062052
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis., PMID:11801725
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation., PMID:11756470
CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells., PMID:11553716
Cytogenetic analysis and construction of a BAC contig across a common neocentromeric region from 9p., PMID:11534819
Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores., PMID:11451998
Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity., PMID:11402067
Evolutionary conservation of kinetochore protein sequences in plants., PMID:11151678
Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere--kinetochore complexes., PMID:11092768
CENP-E as an essential component of the mitotic checkpoint in vitro., PMID:11030625
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint., PMID:10934468
Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins., PMID:10607828
Neocentromere formation in a stable ring 1p32-p36.1 chromosome., PMID:10593999
Conservation of centromere protein in vertebrates., PMID:10461871
Chromosome engineering: generation of mono- and dicentric isochromosomes in a somatic cell hybrid system., PMID:10460414
Symmetric replication of an unstable isodicentric Xq chromosome derived from isolocal maternal sister chromatid recombination., PMID:10405438
Microinjection of antibodies to centromere protein CENP-A arrests cells in interphase but does not prevent mitosis., PMID:9914371
The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis., PMID:9914370
Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E., PMID:9744883
Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres., PMID:9499420
Immunolocalization of alpha-tubulin, gamma-tubulin, and CENP-E in male rat and male mouse meiotic divisions: pathway of meiosis I spindle formation in mammalian spermatocytes., PMID:9520321
Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase., PMID:9391217
CENP-E function at kinetochores is essential for chromosome alignment., PMID:9396744
Variegated aneuploidy in two siblings: phenotype, genotype, CENP-E analysis, and literature review., PMID:9450856
CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment., PMID:9363944
CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II., PMID:9256453
For research use only. Not for human or drug use.
