Catalog No.
RHF69301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, WB: 1:1000-1:2000
Target
ETS-related transcription factor Elf-3, Epithelial-restricted with serine box, JEN, Epithelium-restricted Ets protein ESX, E74-like factor 3, ESX, Epithelium-specific Ets transcription factor 1, ESE-1, ERT, ELF3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P78545
Applications
FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2B34
Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRASG13D colorectal cancer., PMID:40340861
Amelioration of LPS-Induced Jejunum Injury and Mucus Barrier Damage in Mice by IgY Embedded in W/O/W Emulsion., PMID:39767078
Synthesis and biological assessment of chalcone and pyrazoline derivatives as novel inhibitor for ELF3-MED23 interaction., PMID:39641248
SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma., PMID:38030644
Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers., PMID:35963541
ETS transcription factor ESE-1/Elf3 is an independent prognostic factor of survival in HR+HER2+ breast cancer patients., PMID:32562116
ESE-1 Knockdown Attenuates Growth in Trastuzumab-resistant HER2+ Breast Cancer Cells., PMID:29187433
Tissue organization alters gene expression in equine induced trophectoderm cells., PMID:28161437
Autoantibodies and decreased expression of the transcription factor ELF-3 together with increased chemokine pathways support an autoimmune phenotype and altered differentiation in lichen planus located in oral mucosa., PMID:23134363
Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism., PMID:21871131
Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury., PMID:21709667
Transactivation of lung lysozyme expression by Ets family member ESE-1., PMID:17905856
A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands., PMID:15655699
Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1., PMID:12746898
Expression of the ETS transcription factor ELF3 in the retinal pigment epithelium., PMID:12407165
ELF a beta-spectrin is a neuronal precursor cell marker in developing mammalian brain; structure and organization of the elf/beta-G spectrin gene., PMID:12149647
Protein 4.1R binding to eIF3-p44 suggests an interaction between the cytoskeletal network and the translation apparatus., PMID:10887144
Elf3 encodes a novel 200-kD beta-spectrin: role in liver development., PMID:9927192