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Anti-CNTNAP1 Antibody (R2B27)

Catalog #:   RHF65504 Specific References (29) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IHC, WB
Accession: P78357
Overview

Catalog No.

RHF65504

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

Contactin-associated protein 1, p190, NRXN4, CNTNAP1, CASPR, Caspr1, Neurexin-4, Neurexin IV, Caspr

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P78357

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2B27

Data Image
  • Western blot
    Western blot analysis of Caspr expression in U87-MG cell lysate.
References

Anti-contactin-associated protein 1 antibody-positive nodopathy presenting with central nervous system symptoms., PMID:39084134

Leucine-Rich Glioma-Inactivated 1 versus Contactin-Associated Protein-like 2 Antibody Neuropathic Pain: Clinical and Biological Comparisons., PMID:34370313

Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyradiculoneuropathy., PMID:33880507

Peripheral nerve hyperexcitability syndrome: A clinical, electrophysiological, and immunological study., PMID:33501683

Generation of High-Yield, Functional Oligodendrocytes from a c-myc Immortalized Neural Cell Line, Endowed with Staminal Properties., PMID:33498778

Antiparanodal antibodies and IgG subclasses in acute autoimmune neuropathy., PMID:32736337

Antibodies to neurofascin, contactin-1, and contactin-associated protein 1 in CIDP: Clinical relevance of IgG isotype., PMID:31753915

Behaviour and neuropathology in mice injected with human contactin-associated protein 2 antibodies., PMID:31079141

Anti-CNTN1 IgG3 induces acute conduction block and motor deficits in a passive transfer rat model., PMID:30953561

Increased adverse events associated with antiepileptic drugs in anti-leucine-rich glioma-inactivated protein 1 encephalitis., PMID:30159879

Autoantibodies Against the Node of Ranvier in Seropositive Chronic Inflammatory Demyelinating Polyneuropathy: Diagnostic, Pathogenic, and Therapeutic Relevance., PMID:29867996

Brain-relevant antibodies in first-episode psychosis: a matched case-control study., PMID:28920570

IgG4 anti-neurofascin155 antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: Clinical significance and diagnostic utility of a conventional assay., PMID:27852440

Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy., PMID:27474220

Contactin-1 IgG4 antibodies cause paranode dismantling and conduction defects., PMID:27017186

[Morvan's syndrome (Morvan's fibrillary chorea)]., PMID:26480798

Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain., PMID:24685353

Neutralization of inhibitory molecule NG2 improves synaptic transmission, retrograde transport, and locomotor function after spinal cord injury in adult rats., PMID:23447612

Nodes of ranvier and paranodes in chronic acquired neuropathies., PMID:21267074

Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury., PMID:17662136

No effect of genetic deletion of contactin-associated protein (CASPR) on axonal orientation and synaptic plasticity., PMID:17549747

Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve., PMID:16828970

Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning., PMID:16203097

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier., PMID:16039564

Changes in the expression and localization of the paranodal protein Caspr on axons in chronic multiple sclerosis., PMID:12805111

Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres., PMID:12542678

Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction., PMID:11839274

Protein zero is necessary for E-cadherin-mediated adherens junction formation in Schwann cells., PMID:11749037

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination., PMID:11069942

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-CNTNAP1 Antibody (R2B27) [RHF65504]
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