Catalog No.
RHF10901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
CASP7, ICE-LAP3, CASP-7, MCH3, Caspase-7, CMH-1, ICE-like apoptotic protease 3, Apoptotic protease Mch-3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P55210
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Z24
The Qi Yin San Liang San decoction enhances anti-CD19 CAR-T cell function in the treatment of B-cell lymphomas., PMID:37657771
Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity., PMID:31940267
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways., PMID:31730855
Acute pulmonary effects of aerosolized nicotine., PMID:30358437
G-quartet oligonucleotide mediated delivery of functional X-linked inhibitor of apoptosis protein into retinal cells following intravitreal injection., PMID:29864441
Zoledronic acid overcomes chemoresistance by sensitizing cancer stem cells to apoptosis., PMID:29300112
Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model., PMID:28783166
Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia., PMID:27283740
Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death., PMID:27133385
Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 and -7-dependent., PMID:26504199
Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice., PMID:25366368
Targeted elimination of activated hepatic stellate cells by an anti-epidermal growth factor-receptor single chain fragment variable antibody-tumor necrosis factor-related apoptosis-inducing ligand (scFv425-sTRAIL)., PMID:25088657
Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis., PMID:24574456
Myocilin regulates cell proliferation and survival., PMID:24563482
Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock., PMID:24456467
Loss of caspase 7 expression is associated with poor prognosis in renal cell carcinoma clear cell subtype., PMID:23920448
Engineered soluble monomeric IgG1 CH3 domain: generation, mechanisms of function, and implications for design of biological therapeutics., PMID:23867459
BH3 mimetics reduce adhesion and migration of hepatoblastoma and hepatocellular carcinoma cells., PMID:23416067
REST is up-regulated by epidermal growth factor in HeLa cells and inhibits apoptosis by influencing histone H3 acetylation., PMID:22668508
[Role of NF-κB in factor VIIa-induced proliferation and migration of colon cancer cell line SW620 cells]., PMID:22340043
Staurosporine-induced differentiation of the RGC-5 cell line leads to apoptosis and cell death at the lowest differentiating concentration., PMID:22222923
HDAC inhibitors potentiate the apoptotic effect of enzastaurin in lymphoma cells., PMID:21667043
Amyloid beta-mediated cell death of cultured hippocampal neurons reveals extensive Tau fragmentation without increased full-length tau phosphorylation., PMID:21482827
Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner., PMID:20872776
ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis., PMID:20213810
Chemotherapy-induced thrombin generation via procoagulant endothelial microparticles is independent of tissue factor activity., PMID:17922809
Secretory phospholipase A2 induces apoptosis through TNF-alpha and cytochrome c-mediated caspase cascade in murine macrophage RAW 264.7 cells., PMID:16564042
Glucocorticoid modulatory element-binding protein 1 binds to initiator procaspases and inhibits ischemia-induced apoptosis and neuronal injury., PMID:16497673
Relationship between SUMO-1 modification of caspase-7 and its nuclear localization in human neuronal cells., PMID:16378684
Wnt/beta-catenin signaling mediates antineoplastic effects of imatinib mesylate (gleevec) in anaplastic thyroid cancer., PMID:16263821
Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker., PMID:15904507
A novel caspase-7 specific monoclonal antibody., PMID:15849872
p53 potentiation of tumor cell susceptibility to CTL involves Fas and mitochondrial pathways., PMID:15634909
Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling., PMID:15623759
Cleavage of calnexin caused by apoptotic stimuli: implication for the regulation of apoptosis., PMID:15598898
Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells., PMID:15563545
Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone hsp70., PMID:15544164
Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation., PMID:15469933
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells., PMID:15283467
Keratin 8/18 breakdown and reorganization during apoptosis., PMID:15194421
Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin., PMID:14695155
Teratogen-induced activation of caspase-6 and caspase-7 in early postimplantation mouse embryos., PMID:14686614
Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1., PMID:12867998
Ribavirin and alpha interferon enhance death receptor-mediated apoptosis and caspase activation in human hepatoma cells., PMID:12760867
The p54 cleaved form of the tyrosine kinase Lyn generated by caspases during BCR-induced cell death in B lymphoma acts as a negative regulator of apoptosis., PMID:12586738
Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis., PMID:12432255
Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway., PMID:12181741
Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells., PMID:11937545
Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases., PMID:11801463
Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short)., PMID:11585748