Catalog No.
RHF09502
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
GPR11, Thrombin receptor-like 1, G-protein coupled receptor 11, F2RL1, PAR-2, Coagulation factor II receptor-like 1, Proteinase-activated receptor 2, PAR2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P55085
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Z16
House dust mites stimulate thymic stromal lymphopoietin production in human bronchial epithelial cells and promote airway remodeling through activation of PAR2 and ERK signaling pathway., PMID:39562597
FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription., PMID:39060025
Protective role of protease-activated receptor-2 in anaphylaxis model mice., PMID:38635782
A novel trypsin of Trichinella spiralis mediates larval invasion of gut epithelium via binding to PAR2 and activating ERK1/2 pathway., PMID:38166153
Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments., PMID:38007440
Comprehensive analysis of the lncRNAs-related immune gene signatures and their correlation with immunotherapy in lung adenocarcinoma., PMID:37543671
Involvement of kallikrein-PAR2-proinflammatory pathway in severe trastuzumab-induced cardiotoxicity., PMID:35879248
Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain., PMID:35110404
The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment., PMID:34930943
Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: Involvement of interleukin-6., PMID:34430676
The development of proteinase-activated receptor-2 modulators and the challenges involved., PMID:33242065
Protease-activated receptor 2 protects against VEGF inhibitor-induced glomerular endothelial and podocyte injury., PMID:30814628
Factor VIIa-induced interaction with integrin controls the release of tissue factor on extracellular vesicles from endothelial cells., PMID:30740873
Targeting of cathepsin S reduces cystic fibrosis-like lung disease., PMID:30655278
Quail egg homogenate alleviates food allergy induced eosinophilic esophagitis like disease through modulating PAR-2 transduction pathway in peanut sensitized mice., PMID:29348584
Genetics of pleiotropic effects of dexamethasone., PMID:28628558
Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice., PMID:28191683
Proinflammatory genes expression in granulocytes activated by native proteinase-binding fragments of anti-proteinase 3 IgG., PMID:26348085
Up-regulation and activation of proteinase-activated receptor 2 in early and delayed radiation injury in the rat intestine: influence of biological activators of proteinase-activated receptor 2., PMID:14565830
For research use only. Not for human or drug use.
