Catalog No.
RME92801
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
p113, STAT2, Signal transducer and activator of transcription 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9WVL2
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1Y60
Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production., PMID:39879745
Blood transcriptome profiling reveals distinct gene networks induced by mRNA vaccination against COVID-19., PMID:39402787
STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases., PMID:39188021
FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription., PMID:39060025
Elevated unphosphorylated STAT1 and IRF9 in T and B cells of primary sjögren's syndrome: Novel biomarkers for disease activity and subsets., PMID:38788537
The Susceptibility of Chickens to Zika Virus: A Comprehensive Study on Age-Dependent Infection Dynamics and Host Responses., PMID:38675911
Zika purified inactivated virus (ZPIV) vaccine reduced vertical transmission in pregnant immunocompetent mice., PMID:38360793
Immunocompetent mouse models revealed that S100A4+ monocytes/macrophages facilitate long-term Zika virus infection in the testes., PMID:38164719
ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs., PMID:38139463
The NSs protein of severe fever with thrombocytopenia syndrome virus differentially inhibits the type 1 interferon response among animal species., PMID:37187292
Inborn Error of STAT2-Dependent IFN-I Immunity in a Patient Presented with Hemophagocytic Lymphohistiocytosis and Multisystem Inflammatory Syndrome in Children., PMID:37074537
Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2., PMID:36753016
Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus., PMID:36737485
Integrated analysis identifies the IL6/JAK/STAT signaling pathway and the estrogen response pathway associated with the pathogenesis of intracranial aneurysms., PMID:36451838
Phase II clinical and immune correlate study of adjuvant nivolumab plus ipilimumab for high-risk resected melanoma., PMID:36450385
Genetic Diagnosis of Inborn Errors of Immunity in an Emerging Country: a Retrospective Study of 216 Moroccan Patients., PMID:36367635
Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial., PMID:35946107
A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients., PMID:35842705
Transcription Factors and Regulators Pathway-focused Genes Expression Analysis in Patients with Different Forms of Thyroid Pathology., PMID:35176984
HHLA2 Activates the JAK/STAT Signaling Pathway by Binding to TMIGD2 in Hepatocellular Carcinoma Cells., PMID:35175496
Abnormalities of the type I interferon signaling pathway in lupus autoimmunity., PMID:34340046
Evaluating the Safety of West Nile Virus Immunity During Congenital Zika Virus Infection in Mice., PMID:34220838
The protein landscape of chronic lymphocytic leukemia., PMID:34189564
Impact of prior Dengue immunity on Zika vaccine protection in rhesus macaques and mice., PMID:34170962
IFN-β, but not IFN-α, is Responsible for the Pro-Bacterial Effect of Type I Interferon., PMID:33984198
Downregulation of SHANK-associated RH domain-interacting protein elevates interleukin-33 expression by stimulating the Janus kinase 2/signal transducer and activator of transcription signalling pathway in HaCaT cells., PMID:33548083
Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses., PMID:33510473
Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production., PMID:33457079
Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A., PMID:33445752
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1., PMID:33248053
Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models., PMID:32949997
The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9., PMID:32581091
Sunflower seed oil combined with ginseng stem-leaf saponins as an adjuvant to enhance the immune response elicited by Newcastle disease vaccine in chickens., PMID:32571723
Stat2 loss disrupts damage signalling and is protective in acute pancreatitis., PMID:32506441
Cloning and Expression of the Tibetan Pig Interleukin-23 Gene and Its Promotion of Immunity of Pigs to PCV2 Vaccine., PMID:32466622
Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement., PMID:32305868
Identification of molecules associated with response to abatacept in patients with rheumatoid arthritis., PMID:32164778
Monoclonal Antibodies with Neutralizing Activity and Fc-Effector Functions against the Machupo Virus Glycoprotein., PMID:31801871
Influence of elevated protein and tannin-rich peanut skin supplementation on growth performance, blood metabolites, carcass traits and immune-related gene expression of grazing meat goats., PMID:31724236
Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice., PMID:31260518
Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus., PMID:30940710
Differential Innate Immune Responses Elicited by Nipah Virus and Cedar Virus Correlate with Disparate In Vivo Pathogenesis in Hamsters., PMID:30909389
Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in STAT2 KO Syrian Hamsters., PMID:30678320
Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis viruses., PMID:30527622
Analysis of STAT1, STAT2 and STAT3 mRNA expression levels in the blood of patients with multiple sclerosis., PMID:30412483
Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model., PMID:30385750
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction., PMID:30269996
An Immunocompetent Mouse Model of Zika Virus Infection., PMID:29746837
Transcription profiling of peripheral B cells in antibody-positive primary Sjögren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature., PMID:29655283
CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages., PMID:29437254
For research use only. Not for human or drug use.
