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Anti-GCLC Antibody (R1X09)

Catalog #:   RHE58202 Specific References (24) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: WB
Accession: P48506
Overview

Catalog No.

RHE58202

Species reactivity

Human, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

WB: 1:1000-1:2000

Target

Gamma-ECS, GCLC, Gamma-glutamylcysteine synthetase, GCS heavy chain, GLCLC, Glutamate--cysteine ligase catalytic subunit, GLCL

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P48506

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R1X09

Data Image
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of GCLC expression in HepG2 cell lysate.
References

Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells., PMID:35379825

Probucol promotes high glucose-induced proliferation and inhibits apoptosis by reducing reactive oxygen species generation in Müller cells., PMID:31144240

The impact of ganglion cell layer cysts in diabetic macular oedema treated with anti-vascular endothelial growth factor., PMID:31099498

Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells., PMID:28436007

Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress., PMID:27048381

TGFβ1 mediates alcohol-induced Nrf2 suppression in lung fibroblasts., PMID:25421510

Molecular cloning and analysis of Ancylostoma ceylanicum glutamate-cysteine ligase., PMID:25092620

Keap1 inhibition attenuates glomerulosclerosis., PMID:24523358

Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: the role of IL-6 signaling and Nrf2/AKR1C axis identification., PMID:23933386

Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy., PMID:23633659

Epidermal growth factor receptor transactivation is necessary for glucagon-like peptide-1 to protect PC12 cells from apoptosis., PMID:23147408

Molecular mechanisms of early growth response protein-1 (EGR-1) expression by quercetin in INS-1 beta-cells., PMID:22174042

The role of c-Jun phosphorylation in EpRE activation of phase II genes., PMID:19666106

Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1., PMID:18523133

Extract of Ginkgo biloba induces glutamate cysteine ligase catalytic subunit (GCLC)., PMID:18167050

Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries., PMID:18066575

Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels., PMID:17479437

[Effects of benzo(a)pyrene on the expression of gamma-glutamate-cysteine ligase: a primary study with rat alveolar epithelial cells]., PMID:17288842

4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes., PMID:17173895

Identification of an E-box motif as a transcriptional repressor element in the proximal promoter region of the GCLC gene in rat lung epithelial L2 cells., PMID:16198230

[Experimental study of E-box, a transcriptional suppressor element in gamma-GCS gene]., PMID:15949339

Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development., PMID:15336720

Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase., PMID:11909699

Germinal center B cells lack homing receptors necessary for normal lymphocyte recirculation., PMID:6339668

Datasheet

Document Download

Anti-GCLC Antibody (R1X09).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-GCLC Antibody (R1X09) [RHE58202]
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