Catalog No.
RHD38701
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
WB: 1:1000-1:2000
Target
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein, ALOX5AP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P20292
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R1R53
The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses., PMID:30735559
Interstitial lung disease in Systemic sclerosis: insights into pathogenesis and evolving therapies., PMID:32185315
Genetic Predictors of Drug Hypersensitivity., PMID:27779086
The clinical and environmental determinants of airway transcriptional profiles in allergic asthma., PMID:22246175
Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes., PMID:20144213
Increased expression of lipoxygenase enzymes during pollen season in nasal biopsies of pollen-allergic patients., PMID:16677242
Interleukin-18 primes human basophilic KU812 cells for higher leukotriene synthesis., PMID:16280246
Cytosolic phospholipase A2alpha-deficient mice are resistant to collagen-induced arthritis., PMID:12743172
Prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene B4 production from dendritic cells via an IL-10-dependent mechanism., PMID:12496393
Expression of 5-lipoxygenase and 5-lipoxygenase-activating protein in human fetal membranes throughout pregnancy and at term., PMID:10381823
Generation of thromboxane A2 from highly purified human sinus mast cells after immunological stimulation., PMID:10359019
Differential leukotriene constrictor responses in human atherosclerotic coronary arteries., PMID:9641692
Production of leukotriene C4 in different human tissues is attributable to distinct membrane bound biosynthetic enzymes., PMID:9092565
Collagen-induced arthritis is reduced in 5-lipoxygenase-activating protein-deficient mice., PMID:9091585
Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses., PMID:9091580
The importance of leukotrienes in airway inflammation in a mouse model of asthma., PMID:8879219
Lymphocytes stimulate expression of 5-lipoxygenase and its activating protein in monocytes in vitro via granulocyte macrophage colony-stimulating factor and interleukin 3., PMID:8636442
Lipoxygenase products and expression of 5-lipoxygenase and 5-lipoxygenase-activating protein in human cultured synovial cells., PMID:8750209
Expression cloning of human LTC4 synthase., PMID:7732869
5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes., PMID:8245774
5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors., PMID:1857337
For research use only. Not for human or drug use.
